Tyrosine decarboxylase is an enzyme that catalyzes the decarboxylation of tyrosine to produce tyramine, a biogenic amine. This enzyme plays a crucial role in the biosynthesis of catecholamines, which are important neurotransmitters in the nervous system. Tyrosine decarboxylase is typically found in various organisms, including bacteria and plants, and is particularly significant in the context of microbial metabolism. The enzyme operates optimally at specific pH and temperature ranges, which can vary depending on the source organism. It is a member of the class of enzymes known as lyases, specifically carboxy-lyases, which facilitate the removal of carboxyl groups from amino acids. The activity of tyrosine decarboxylase can be influenced by various factors, including substrate concentration, the presence of cofactors, and regulatory molecules. Understanding this enzyme is important for its potential applications in biotechnology and medicine, particularly in the study of neurotransmitter synthesis and related disorders.

Tyrosine decarboxylase

9002-09-9: Tyrosine decarboxylase is an enzyme that catalyzes the decarboxylation of tyrosine to produce tyramine, a biogenic amine. This enzyme plays a crucial role in the biosynthesis of catecholamines, which are important neurotransmitters in the nervous system. Tyrosine decarboxylase is typically found in various organisms, including bacteria and plants, and is particularly significant in the context of microbial metabolism. The enzyme operates optimally at specific pH and temperature ranges, which can vary depending on the source organism. It is a member of the class of enzymes known as lyases, specifically carboxy-lyases, which facilitate the removal of carboxyl groups from amino acids. The activity of tyrosine decarboxylase can be influenced by various factors, including substrate concentration, the presence of cofactors, and regulatory molecules. Understanding this enzyme is important for its potential applications in biotechnology and medicine, particularly in the study of neurotransmitter synthesis and related disorders.

<p>TDC, a PLP-dependent enzyme, removes carboxyl groups from tyrosine, producing tyramine and CO2, found in plants, insects, and microbes.</p>

CAS 9002-09-9

Tyrosine decarboxylase

Tyrosine decarboxylase

Ref: TM-T73614