CAS 90029-73-5

(2E)-3-(6-amino-9H-purin-9-yl)prop-2-enal

Description:

The chemical substance known as (2E)-3-(6-amino-9H-purin-9-yl)prop-2-enal, with the CAS number 90029-73-5, is a purine derivative characterized by its structural features that include a purine base linked to an aldehyde functional group through a prop-2-enal moiety. This compound exhibits properties typical of purines, such as the ability to participate in hydrogen bonding due to the presence of amino and carbonyl groups, which can influence its reactivity and interactions in biological systems. The presence of the double bond in the prop-2-enal portion suggests potential for electrophilic reactions, making it a candidate for various chemical transformations. Additionally, its amino group may contribute to its solubility in polar solvents and its biological activity, potentially influencing nucleic acid metabolism or serving as a precursor in biochemical pathways. Overall, this compound's unique structure positions it as a significant molecule in both synthetic and biological chemistry contexts.

Formula: C₈H₇N₅O

InChI: InChI=1/C8H7N5O/c9-7-6-8(11-4-10-7)13(5-12-6)2-1-3-14/h1-5H,(H2,9,10,11)/b2-1+

Synonyms:

• 2-propenal, 3-(6-amino-9H-purin-9-yl)-, (2E)-
• 9-(3-Oxoprop-1-Enyl)Adenine

3-(6-Amino-9H-purin-9-yl)-2-propenal-13C, 15N2

Controlled Product

CAS: 90029-73-5

Formula: CC₇H₇₁₅N₂N₃O

Color and Shape: Neat

Molecular weight: 192.154

Ref: TR-A628883

3-(6-Amino-9H-purin-9-yl)-2-propenal

Controlled Product

CAS: 90029-73-5

Applications 3-(6-Amino-9H-purin-9-yl)-2-propenal is considered as one of the major sources of endogenous M1dG adducts in cellular DNA. If not repaired, these adducts are mutagenic and carcinogenic.
References Zhou, X., et al.: J. Biol. Chem., 280, 25377 (2005);

Formula: C₈H₇N₅O

Color and Shape: Neat

Molecular weight: 189.174

Ref: TR-A628880

3-(6-Amino-9H-purin-9-yl)-2-propenal-13C3

Controlled Product

CAS: 90029-73-5

Formula: C₃C₅H₇N₅O

Color and Shape: Neat

Molecular weight: 192.152

Ref: TR-A628882