Elastase, with the CAS number 9004-06-2, is a serine protease enzyme primarily involved in the breakdown of elastin, a key protein in connective tissues. It is produced by various organisms, including humans, where it plays a crucial role in the immune response and tissue remodeling. Elastase exhibits specificity for peptide bonds adjacent to small, hydrophobic amino acids, facilitating the degradation of elastin and other proteins. This enzyme is typically found in the pancreas and is secreted into the small intestine, where it aids in protein digestion. Elastase is also utilized in various biotechnological applications, including research and therapeutic contexts, due to its ability to cleave specific peptide bonds. Its activity can be influenced by factors such as pH and temperature, and it may be inhibited by specific inhibitors, which are important in regulating its function in biological systems. Overall, elastase is significant in both physiological processes and potential clinical applications, particularly in understanding diseases related to connective tissue degradation.

Elastase

9004-06-2: Elastase, with the CAS number 9004-06-2, is a serine protease enzyme primarily involved in the breakdown of elastin, a key protein in connective tissues. It is produced by various organisms, including humans, where it plays a crucial role in the immune response and tissue remodeling. Elastase exhibits specificity for peptide bonds adjacent to small, hydrophobic amino acids, facilitating the degradation of elastin and other proteins. This enzyme is typically found in the pancreas and is secreted into the small intestine, where it aids in protein digestion. Elastase is also utilized in various biotechnological applications, including research and therapeutic contexts, due to its ability to cleave specific peptide bonds. Its activity can be influenced by factors such as pH and temperature, and it may be inhibited by specific inhibitors, which are important in regulating its function in biological systems. Overall, elastase is significant in both physiological processes and potential clinical applications, particularly in understanding diseases related to connective tissue degradation.

<p>Elastase (EC 3.4. 21.36) is a serine protease that breaks down elastin fibers. One unit of Elastase release 1 nmol of p-nitrophenol per sec from BOC-L-alanine p-nitrophenyl ester at pH 6.5 and 37°C</p>

CAS 9004-06-2

Elastase

Elastase

Ref: 3D-OE182110