CAS 9004-54-0

Dextran

Description:

Dextran is a complex branched polysaccharide composed of glucose units linked primarily by α(1→6) glycosidic bonds, with occasional α(1→3) linkages. It is produced by certain bacteria, such as Leuconostoc mesenteroides, and is commonly used in various applications due to its biocompatibility and non-toxicity. Dextran is soluble in water, forming a viscous solution, and exhibits a high molecular weight, which can vary depending on the source and method of production. Its properties include being a stabilizer, thickening agent, and a medium for drug delivery in pharmaceuticals. Additionally, dextran is utilized in the food industry as a food additive and in medical applications, such as in blood volume expanders and as a component in diagnostic tests. Its ability to form gels and its low immunogenicity make it valuable in biotechnology and research. Overall, dextran's versatility and safety profile contribute to its widespread use across multiple fields.

Formula: Unspecified

Synonyms:

• Cdc-H
• Dextran11
• Dextran2
• Dextran5
• Dextranen
• DextrangradeA,B,C
• Dextrano
• Dextrans
• Dextraven
• Eudextran
• Ex-pandex
• Expandex
• Gentran
• Gentran3
• Hemodex
• Hyscon
• Hyskon
• Infucoll
• Intrader
• Intradex
• LMD
• LVD
• Lmwd
• Macrodex
• Macrose
• Mucrose
• Onkotin
• Plasmafusin
• Plasmodex
• Plavolex
• Polyglucin
• Polyglusol
• Promit
• R-gel
• Rheodextran
• Rheoisodex
• Rheomacrodex
• Rheopolyglucin
• Rheopolyglucine
• Rheorondex
• Rheotran
• Rondex
• Ultradex
• α-Dextran
• Dextran 70
• Dextran 40
• Glucose polymer
• Dextran 45

Dextran (MW 5000)

CAS: 9004-54-0

Dextran (MW 5000) has an inhibitory effect on platelet aggregation and coagulation factors, and is used as an agent for increasing plasma volume.

Formula: (C₆H₁₀O₅)n

Purity: ≥98%

Color and Shape: Solid

Molecular weight: 64000-76000

Ref: TM-T11012

Dextran 70 - MW 64,000 to 76,000, EP

CAS: 9004-54-0

Complex glucan (a 1-6) from Leuconostoc spp.; extender in blood transfusions.

Purity: Min. 95%

Ref: 3D-YD172635

Dextran (Technical Grade~ 100K)

CAS: 9004-54-0

Applications Dextran is a polysaccharide composed of glucose molecules used as an antithrombotic to reduce blood viscosity and as a volume expander in anemia. Studies show that it inhibits the mannose receptor-mediated clearance of tissue-type plasminogen activator (t-PA).
References MacNeil, B.D. et al.: Fund. Clin. Cardiol., 52, 473 (2005); Noorman, F. et al.: Thromb. Haemost., 80, 210 (1998); Fushbane, S. et al.: Am. J. Kidney Dis., 28, 529 (1996);

Formula: H₂(C₆H₉O₅)n(C₇H₁₂O₅)mOH

Color and Shape: Neat

Molecular weight: 504.4

Ref: TR-D299130

Dextran 40 System Suitability

CAS: 9004-54-0

Chemical derivatives of natural rubber

Formula: (C₆H₁₀O₅)n

Color and Shape: White Amorphous Powder

Molecular weight: 39000 - 46000

Ref: 45-1179720

Dextran 70 System Suitability

CAS: 9004-54-0

Chemical derivatives of natural rubber

Formula: (C₆H₁₀O₅)n

Color and Shape: White Powder

Molecular weight: 65000 - 74000

Ref: 45-1179763

Dextran T-10

CAS: 9004-54-0

Chemical derivatives of natural rubber

Formula: (C₆H₁₀O₅)n

Color and Shape: White Fine Powder

Molecular weight: 123.1525

Ref: 45-1179650

Dextran 110, MW: 100,000 to 120,000

CAS: 9004-54-0

Complex glucan (a 1-6) from Leuconostoc spp.; extender in blood transfusions.

Color and Shape: White Powder

Ref: 3D-OD156909

Dextran 60, MW: 54,000 to 66,000

CAS: 9004-54-0

Complex glucan (a 1-6) from Leuconostoc spp.; extender in blood transfusions

Formula: (C₆H₁₀O₅)n

Color and Shape: White Powder

Ref: 3D-OD156910

Dextran 750 - MW: 500,000 to 1,000,000

CAS: 9004-54-0

Dextran is a polysaccharide that is used as an antimicrobial agent and as a volume expander in the treatment of bowel disease, myocardial infarct, and other diseases. Dextran sulfate is a linear polymer with a molecular weight of 500,000 to 1,000,000. It has minimal toxicity and does not interfere with iron homeostasis or cause fluid overload. Dextran sulfate can be used for the treatment of bowel disease because it has been shown to have anti-inflammatory effects in experimental models. The mechanism by which dextran sulfate inhibits inflammation is unknown, but may involve its ability to bind to macrophages and neutrophils in the gut wall. Dextran sulfate also binds to bacteria and prevents their growth. This binding may prevent bacterial penetration into epithelial cells or block bacterial attachment to cell surfaces. The efficacy of dextran sulfate against pathogenic mechanisms such as inflammation has been demonstrated in experimental models.

Purity: Min. 95%

Color and Shape: White Powder

Ref: 3D-OD156906

Dextran 250 - MW: 225,000 to 275,000

CAS: 9004-54-0

Complex glucan (a 1-6) from Leuconostoc spp.; extender in blood transfusions

Color and Shape: Powder

Ref: 3D-OD156911

Dextran 150 - MW: 135,000 to 165,000

CAS: 9004-54-0

Complex glucan (a 1-6) from Leuconostoc spp.; extender in blood transfusions

Color and Shape: Powder

Ref: 3D-OD156908

Dextran 2000 - MW: 1,500,000 to 3,500,000

CAS: 9004-54-0

Dextran 2000 is a high molecular weight biocompatible polymer with transport properties. It is used in a variety of medical applications, such as red blood cell transfusions and the prevention of post-surgical adhesions. Dextran 2000 has been shown to be a safe and effective means of preventing hemolysis during red blood cell transfusion. This agent binds to amine groups on the surface of erythrocytes, which prevents complement activation and subsequent lysis. Additionally, dextran 2000 has been shown to exhibit low cytotoxicity against neuronal cells in vitro.

Purity: Min. 95%

Color and Shape: White Off-White Powder

Ref: 3D-OD156913

Dextran 20, MW: 17,000 to 23,000

CAS: 9004-54-0

Complex glucan (a 1-6) from Leuconostoc spp.; extender in blood transfusions

Color and Shape: Powder

Ref: 3D-OD156907