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CAS 9005-27-0

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Hydroxyethyl starch

Description:
Hydroxyethyl starch (HES), with the CAS number 9005-27-0, is a synthetic polymer derived from starch, commonly used in medical and pharmaceutical applications. It is characterized by its ability to increase blood volume and maintain plasma volume, making it valuable as a volume expander in intravenous fluid therapy. HES is soluble in water and exhibits a low viscosity, which facilitates its use in various formulations. The degree of hydroxyethylation can vary, influencing its molecular weight and pharmacokinetic properties. HES is generally well-tolerated, but its use has been associated with potential side effects, particularly in patients with renal impairment or those undergoing critical care. Its safety profile has led to regulatory scrutiny, and guidelines for its use have been established to minimize risks. Additionally, HES can be modified to enhance its properties for specific applications, including drug delivery systems and as a stabilizing agent in various formulations. Overall, hydroxyethyl starch is a versatile compound with significant applications in medicine and pharmaceuticals.
Formula:(C6H10O5)m(C2H5O)n
InChI:InChI=1/C16H32O11.C6H12O6/c17-1-6-22-11-12-13(23-7-2-18)14(24-8-3-19)15(25-9-4-20)16(27-12)26-10-5-21;7-1-2-3(8)4(9)5(10)6(11)12-2/h12-21H,1-11H2;2-11H,1H2/t12-,13-,14+,15-,16+;2-,3-,4+,5-,6+/m11/s1
Synonyms:
  • Bohramyl
  • Elohast
  • Elohes
  • Expafusin
  • Expafusion
  • HAES-steril
  • HET
  • Hemoes
  • Hespan
  • Hespander
  • See more synonyms
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