CAS 90053-16-0

3'-amino-3'-deoxythymidine 5'-(tetrahydrogen triphosphate)

Description:

3'-Amino-3'-deoxythymidine 5'-(tetrahydrogen triphosphate), commonly referred to as dATP analog, is a nucleotide analog that plays a significant role in biochemical research and applications. This compound features an amino group at the 3' position of the deoxythymidine backbone, which distinguishes it from natural nucleotides. The presence of the triphosphate group is crucial for its function in enzymatic reactions, particularly in DNA synthesis and polymerization processes. The structural modifications impart unique properties, such as altered binding affinities and potential inhibitory effects on DNA polymerases, making it a valuable tool in molecular biology. Its CAS number, 90053-16-0, identifies this specific compound in chemical databases. The compound is typically used in studies involving DNA replication, repair mechanisms, and as a substrate in various enzymatic assays. Overall, 3'-amino-3'-deoxythymidine 5'-(tetrahydrogen triphosphate) serves as an important analog for understanding nucleotide interactions and the dynamics of nucleic acid metabolism.

Formula: C₁₀H₁₈N₃O₁₃P₃

InChI: InChI=1/C10H18N3O13P3/c1-5-3-13(10(15)12-9(5)14)8-2-6(11)7(24-8)4-23-28(19,20)26-29(21,22)25-27(16,17)18/h3,6-8H,2,4,11H2,1H3,(H,19,20)(H,21,22)(H,12,14,15)(H2,16,17,18)/t6-,7+,8+/m0/s1

3'-Amino-2',3'-dideoxythymidine-5'-triphosphate lithium salt - 100 mM aqueous solution

CAS: 90053-16-0

3'-Amino-2',3'-dideoxythymidine-5'-triphosphate lithium salt - 100 mM aqueous solution is the sodium salt of the monophosphate ester of 3'-amino-2',3'-dideoxy-5'-thiacytidine. It is used as an antiviral and antineoplastic agent. 3'-Amino-2',3'-dideoxythymidine-5'-triphosphate lithium salt - 100 mM aqueous solution has been shown to be an activator of RNA polymerase II and DNA polymerase, which are enzymes that synthesize proteins and DNA, respectively. This drug also inhibits the synthesis of deoxyribonucleosides, diphosphates, and nucleosides. END>

Formula: C₁₀H₁₈N₃O₁₃P₃(freeacid)

Purity: Min. 95%

Color and Shape: Clear Liquid

Molecular weight: 481.18 g/mol

Ref: 3D-NA71667