CAS 90053-17-1

Cytidine 5'-(tetrahydrogen triphosphate), 3'-amino-2',3'-dideoxy-

Description:

Cytidine 5'-(tetrahydrogen triphosphate), 3'-amino-2',3'-dideoxy- is a nucleotide analog that plays a significant role in biochemical research, particularly in studies involving nucleic acid synthesis and enzyme interactions. This compound features a cytidine base, which is a pyrimidine nucleoside, linked to a triphosphate group, making it a nucleotide. The presence of the 3'-amino and 2',3'-dideoxy modifications indicates that it lacks a hydroxyl group at the 2' and 3' positions of the ribose sugar, which can influence its reactivity and interactions with enzymes, such as polymerases. These structural characteristics make it a useful tool in molecular biology for studying DNA and RNA processes, as well as for potential therapeutic applications. The CAS number 90053-17-1 uniquely identifies this compound in chemical databases, facilitating its recognition and study in various scientific contexts. Overall, this nucleotide analog is valuable for understanding nucleic acid metabolism and developing antiviral or anticancer strategies.

Formula: C₉H₁₇N₄O₁₂P₃

3'-Amino-2',3'-dideoxycytidine-5'-triphosphate lithium salt - 100 mM aqueous solution

CAS: 90053-17-1

3'-Amino-2',3'-dideoxycytidine's lack of a 3'-hydroxyl group makes it a chain terminator for DNA polymerase, a key application in Sanger sequencing. Additionally, the 3'-amino group serves as a functional handle for modifying the 3' end of oligonucleotides with various labels or conjugates, expanding their utility in research and diagnostics. The lithium salt ensures better handling and solubility.

Formula: C₉H₁₇N₄O₁₂P₃(freeacid)

Purity: Min. 95%

Color and Shape: Clear Liquid

Molecular weight: 466.17 g/mol

Ref: 3D-NA71665