Calcitonin is a peptide hormone primarily produced by the parafollicular cells (C cells) of the thyroid gland in humans and other mammals. It plays a crucial role in calcium homeostasis by lowering blood calcium levels, primarily through its action on bone and kidney. Calcitonin inhibits osteoclast activity, which reduces bone resorption, and promotes renal excretion of calcium. The substance is characterized by its relatively small size, consisting of 32 amino acids in its human form, and it exhibits a high degree of specificity for its receptor, which is a G-protein coupled receptor. Calcitonin is often used therapeutically in conditions such as osteoporosis and Paget's disease due to its ability to counteract bone loss. The CAS number 9007-12-9 refers to a specific formulation or preparation of calcitonin, which may include variations in its source or method of production. Overall, calcitonin is significant in both physiological regulation and clinical applications related to calcium metabolism.

calcitonin

9007-12-9: Calcitonin is a peptide hormone primarily produced by the parafollicular cells (C cells) of the thyroid gland in humans and other mammals. It plays a crucial role in calcium homeostasis by lowering blood calcium levels, primarily through its action on bone and kidney. Calcitonin inhibits osteoclast activity, which reduces bone resorption, and promotes renal excretion of calcium. The substance is characterized by its relatively small size, consisting of 32 amino acids in its human form, and it exhibits a high degree of specificity for its receptor, which is a G-protein coupled receptor. Calcitonin is often used therapeutically in conditions such as osteoporosis and Paget's disease due to its ability to counteract bone loss. The CAS number 9007-12-9 refers to a specific formulation or preparation of calcitonin, which may include variations in its source or method of production. Overall, calcitonin is significant in both physiological regulation and clinical applications related to calcium metabolism.

CAS 9007-12-9

calcitonin