CAS 90105-47-8

H-Ala-Ala-Pro-Val-chloromethylketone

Description:

H-Ala-Ala-Pro-Val-chloromethylketone, also known by its CAS number 90105-47-8, is a synthetic peptide derivative that features a chloromethylketone functional group. This compound is characterized by its structure, which includes the amino acids alanine (Ala), proline (Pro), and valine (Val) linked together in a specific sequence. The presence of the chloromethylketone moiety suggests that it may exhibit reactivity towards nucleophiles, making it useful in biochemical applications, particularly in the study of enzyme inhibition or as a tool for peptide synthesis. The compound is typically utilized in research settings, particularly in the fields of biochemistry and molecular biology, where it may serve as a substrate or inhibitor for various proteolytic enzymes. Its stability, solubility, and reactivity can vary depending on the conditions of use, such as pH and temperature. As with many peptide derivatives, handling should be done with care, considering potential biological activity and safety protocols.

Formula: C₁₇H₂ClN₄O₄

Synonyms:

• Ala-Ala-Pro-Val-Cmk

H-Ala-Ala-Pro-Val-chloromethylketone

CAS: 90105-47-8

H-Ala-Ala-Pro-Val-chloromethylketone is a hydrogen peroxide prodrug that is activated by the enzyme chloromethyl ketone. This drug has been shown to be active against schistosoma and pancreatic cancer cells, as well as in activating peroxide. HAPV may also have an effect on immunity and leukocytes, which could be due to its ability to sensitize these cells to damage caused by other agents, or through the hydrolytic enzymes it generates.

Formula: C₁₇H₂₉ClN₄O₄

Purity: Min. 95%

Molecular weight: 388.89 g/mol

Ref: 3D-FA111004