Citrate lyase, with the CAS number 9012-83-3, is an enzyme that plays a crucial role in cellular metabolism, particularly in the conversion of citrate into acetyl-CoA and oxaloacetate. This enzyme is primarily found in the mitochondria of cells and is involved in the citric acid cycle, facilitating the utilization of citrate derived from carbohydrates and fats. Citrate lyase is a key player in lipid biosynthesis and energy production, making it significant in metabolic pathways. The enzyme operates through a mechanism that involves the cleavage of citrate, which is a six-carbon compound, into two smaller molecules. It is typically characterized by its dependence on co-factors such as ATP and is regulated by various metabolic signals, reflecting the energy status of the cell. Citrate lyase is of interest in research related to metabolic disorders and cancer, as its activity can influence the balance between energy production and biosynthetic processes. Understanding its characteristics and functions can provide insights into metabolic regulation and potential therapeutic targets.

Citrate lyase

9012-83-3: Citrate lyase, with the CAS number 9012-83-3, is an enzyme that plays a crucial role in cellular metabolism, particularly in the conversion of citrate into acetyl-CoA and oxaloacetate. This enzyme is primarily found in the mitochondria of cells and is involved in the citric acid cycle, facilitating the utilization of citrate derived from carbohydrates and fats. Citrate lyase is a key player in lipid biosynthesis and energy production, making it significant in metabolic pathways. The enzyme operates through a mechanism that involves the cleavage of citrate, which is a six-carbon compound, into two smaller molecules. It is typically characterized by its dependence on co-factors such as ATP and is regulated by various metabolic signals, reflecting the energy status of the cell. Citrate lyase is of interest in research related to metabolic disorders and cancer, as its activity can influence the balance between energy production and biosynthetic processes. Understanding its characteristics and functions can provide insights into metabolic regulation and potential therapeutic targets.

Citrate lyase (also known as ATP citrate synthase, EC 2.3.3.8) is an enzyme that catalyzes the following reaction:citrate + ATP + CoA → oxaloacetate + Acetyl-CoA + ADP + Pi

Cytrate Lyase, freeze-dried, Klebsiella Pneumoniae

Citrate lyase (also known as ATP citrate synthase, EC 2.3.3.8) is an enzyme that catalyzes the following reaction:citrate + ATP + CoA → oxaloacetate + Acetyl-CoA + ADP + PiEnzymatic activity: One unit will convert 1.0 micromole of citrate to oxalacetate per minute at pH 7.6 and 25 °C in the presence of required cofactors. Citrate lyase is supplied lyophylized, with activity ≥0.20 unit/mg solid.

CAS 9012-83-3

Citrate lyase

Cytrate Lyase, freeze-dried, Klebsiella Pneumoniae

Ref: 3D-ETS013.6

Citrate lyase from klebsiella pneumonia ≥0.20 unit/mg solid

Ref: 3D-JAA01283