CAS 901245-65-6

GSK5959

CAS: 901245-65-6

Formula: C₂₂H₂₆N₄O₃

Purity: 99%

Molecular weight: 394.4668

Ref: IN-DA00GU8K

GSK-5959

CAS: 901245-65-6

GSK-5959

Purity: ≥98%

Molecular weight: 394.47g/mol

Ref: 54-BUP10643

GSK-5959

CAS: 901245-65-6

GSK-5959 is a selective BRPF1 inhibitor with IC50 ~80 nM, 100-fold more specific than 35 other bromodomains.

Formula: C₂₂H₂₆N₄O₃

Purity: 98.35% - 98.65%

Color and Shape: Solid

Molecular weight: 394.47

Ref: TM-T1972

GSK5959

CAS: 901245-65-6

GSK5959 is a modified heterocycle that binds to the bromodomains of the E3 ubiquitin ligase, preventing the ubiquitination and degradation of target proteins. This compound has been shown to inhibit proliferation in cells with low levels of p27Kip1 protein, which is involved in cell cycle arrest, and can be used as an anti-cancer agent. GSK5959 has also been shown to have a variety of other applications, including inhibition of phosphorylation at Thr638, Thr639, Thr641 and Ser643 on histone H3 (H3T6S) and inhibition of phosphorylation at Thr202/Thr205 on histone H2A (H2AT202/205).

Formula: C₂₂H₂₆N₄O₃

Purity: Min. 95%

Molecular weight: 394.47 g/mol

Ref: 3D-BLB24565