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CAS 90141-22-3

:

(-)-Gossypol

Description:
(-)-Gossypol is a naturally occurring polyphenolic compound primarily derived from the seeds and leaves of the cotton plant (Gossypium species). It is characterized by its yellowish color and is known for its complex structure, which includes multiple aromatic rings and hydroxyl groups. This compound exhibits a range of biological activities, including antifungal, antibacterial, and antiviral properties, and has been studied for its potential use in cancer therapy due to its ability to inhibit cell proliferation and induce apoptosis in certain cancer cell lines. (-)-Gossypol is also recognized for its role as a male contraceptive agent, as it can affect sperm production and motility. However, its use is limited by its toxicity and potential side effects, necessitating careful consideration in therapeutic applications. The compound is soluble in organic solvents but has limited solubility in water, which influences its bioavailability and pharmacokinetics. Overall, (-)-Gossypol is a compound of significant interest in both medicinal chemistry and agricultural research.
Formula:C30H30O8
InChI:InChI=1S/C30H30O8/c1-11(2)19-15-7-13(5)21(27(35)23(15)17(9-31)25(33)29(19)37)22-14(6)8-16-20(12(3)4)30(38)26(34)18(10-32)24(16)28(22)36/h7-12,33-38H,1-6H3
InChI key:InChIKey=QBKSWRVVCFFDOT-UHFFFAOYSA-N
SMILES:C(C)(C)C=1C2=C(C(C=O)=C(O)C1O)C(O)=C(C(C)=C2)C3=C(O)C4=C(C=C3C)C(C(C)C)=C(O)C(O)=C4C=O
Synonyms:
  • (-)-Gossypol
  • (2R)-1,1′,6,6′,7,7′-Hexahydroxy-3,3′-dimethyl-5,5′-bis(1-methylethyl)[2,2′-binaphthalene]-8,8′-dicarboxaldehyde
  • (R)-(-)-Gossypol
  • At 101
  • Sml 0433
  • [2,2'-Binaphthalene]-8,8'-dicarboxaldehyde,1,1',6,6',7,7'-hexahydroxy-3,3'-dimethyl-5,5'-bis(1-methylethyl)-, (R)-
  • [2,2′-Binaphthalene]-8,8′-dicarboxaldehyde, 1,1′,6,6′,7,7′-hexahydroxy-3,3′-dimethyl-5,5′-bis(1-methylethyl)-, (2R)-
  • [2,2′-Binaphthalene]-8,8′-dicarboxaldehyde, 1,1′,6,6′,7,7′-hexahydroxy-3,3′-dimethyl-5,5′-bis(1-methylethyl)-, (R)-
  • C:C&B61
  • DL-gossypol acetic acid
  • See more synonyms
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Found 1 products.
  • AT 101
    Biosynth
    + Info

    AT 101

    CAS:
    <p>AT-101 is a natural compound that belongs to the group of complex enzymes. It has been shown to have a number of physiological effects on plants, including inhibition of cotton fiber elongation and seed development. AT-101 also inhibits hyperproliferative disease in animals. The binding form of AT-101 is bound through hydrolysis to its target enzyme and does not depend on caspase activity for cell death. This makes it an attractive candidate for treating cancer cells that are resistant to apoptosis induced by caspases. AT-101 has been shown to inhibit energy metabolism in insects, which may be due to its ability to bind ATP synthase and prevent ATP production. This can lead to insect resistance against toxic compounds such as gossypol or other pharmacological agents.</p>
    Formula:C30H30O8
    Purity:Min. 95%
    Molecular weight:518.56 g/mol

    Ref: 3D-QDA14122

    50mg
    707.00€
    100mg
    1,010.00€