CAS 902137-22-8

5-(2,4-Dimethylphenyl)-1,3,4-oxadiazol-2-amine

CAS: 902137-22-8

5-(2,4-Dimethylphenyl)-1,3,4-oxadiazol-2-amine is a potent and selective small molecule antagonist of the N-methyl-D-aspartate receptor (NMDAR). It inhibits the neurotoxic effects of glutamate on neurons in vitro. This compound has been used as a research tool to study the role of NMDA receptors in neuronal cell death and to investigate the development of novel therapies for Alzheimer's disease. 5-(2,4-Dimethylphenyl)-1,3,4-oxadiazol-2-amine binds to the NMDAR at a site distinct from that occupied by MK801 and other channel blockers.

Formula: C₁₀H₁₁N₃O

Purity: Min. 95%

Molecular weight: 189.21 g/mol

Ref: 3D-CLB13722