CAS 902146-43-4

(2S)-N,N-Dimethyl-2-(phenylmethyl)-1-aziridinesulfonamide

Description:

(2S)-N,N-Dimethyl-2-(phenylmethyl)-1-aziridinesulfonamide is a chemical compound characterized by its aziridine ring, which is a three-membered cyclic amine. The presence of a sulfonamide group contributes to its potential biological activity, as sulfonamides are known for their antibacterial properties. The dimethylamino group enhances its solubility and reactivity, while the phenylmethyl substituent provides steric bulk and may influence its interaction with biological targets. This compound is likely to exhibit chirality due to the presence of the stereocenter at the aziridine carbon, which can affect its pharmacological properties. Additionally, the aziridine structure may allow for unique reactivity patterns, such as ring-opening reactions, which can be exploited in synthetic chemistry. Overall, this compound's unique structural features suggest potential applications in medicinal chemistry and drug development, particularly in the design of novel therapeutics.

Formula: C₁₁H₁₆N₂O₂S

InChI: InChI=1S/C11H16N2O2S/c1-12(2)16(14,15)13-9-11(13)8-10-6-4-3-5-7-10/h3-7,11H,8-9H2,1-2H3/t11-,13?/m0/s1

InChI key: InChIKey=BLDWVIFYJWKNPQ-AMGKYWFPSA-N

SMILES: C([C@@H]1N(S(N(C)C)(=O)=O)C1)C2=CC=CC=C2

Synonyms:

• (2S)-2-Benzyl-N,N-dimethylaziridine-1-sulfonamide
• (2S)-N,N-Dimethyl-2-(phenylmethyl)-1-aziridinesulfonamide
• (S)-2-benzyl-N,N-dimethylaziridine-1-solfonamide
• 1-Aziridinesulfonamide, N,N-dimethyl-2-(phenylmethyl)-, (2S)-
• BDS
• N,N-Dimethyl-2-benzyl-(2S)-1-aziridinesulfonamide
• (S)-2-Benzyl-N,N-dimethylaziridine-1-sulfonamide

(S)-2-Benzyl-N,N-dimethylaziridine-1-sulfonamide

CAS: 902146-43-4

Formula: C₁₁H₁₆N₂O₂S

Purity: 96%

Color and Shape: Solid

Molecular weight: 240.3219

Ref: IN-DA006IO8

(2S)-2-benzyl-N,N-dimethylaziridine-1-sulfonamide

CAS: 902146-43-4

Purity: ≥96%

Molecular weight: 240.3200073

Ref: 10-F603374

(S)-2-Benzyl-N,N-dimethylaziridine-1-sulfonamide

Controlled Product

CAS: 902146-43-4

Applications (S)-2-Benzyl-N,N-dimethylaziridine-1-sulfonamide is a reagent for the synthesis of N-alkylsulfamic acid derivatives. It also has utility for preparing pharmaceutical peptide analog agents.
References Sherman, E. S., et al. Science of Synthesis 40b, 1285 (2008); Polniaszek, R., et al.: PCT Int. Appl. WO 2010115000 A2 20101007 (2010)

Formula: C₁₁H₁₆N₂O₂S

Color and Shape: Neat

Molecular weight: 240.32

Ref: TR-B251450