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CAS 9024-25-3

:

aconitase from porcine heart

Description:
Aconitase from porcine heart, with the CAS number 9024-25-3, is an enzyme that plays a crucial role in the citric acid cycle (Krebs cycle), facilitating the conversion of citrate to isocitrate through a two-step process involving cis-aconitate as an intermediate. This enzyme is a member of the aconitase family and is characterized by its iron-sulfur cluster, which is essential for its catalytic activity. Aconitase exhibits both enzymatic and regulatory functions, responding to cellular energy levels and influencing metabolic pathways. It is typically found in the mitochondria of cells, where it contributes to energy production. The enzyme is sensitive to oxidative stress, which can lead to the inactivation of its iron-sulfur cluster, thereby affecting its function. Aconitase is also studied for its potential implications in various diseases, including cancer and neurodegenerative disorders, due to its role in metabolic regulation and cellular signaling. Overall, aconitase from porcine heart is a vital enzyme with significant implications in biochemistry and cellular metabolism.
Synonyms:
  • Hydratase, aconitate
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