Nitrilase, with the CAS number 9024-90-2, is an enzyme that catalyzes the hydrolysis of nitriles to their corresponding carboxylic acids and ammonia. This enzyme is classified under the hydrolases category, specifically those acting on carbon-nitrogen bonds. Nitrilases are typically found in various microorganisms and play a crucial role in nitrogen metabolism, allowing these organisms to utilize nitriles as a nitrogen source. The enzyme operates optimally under specific pH and temperature conditions, which can vary depending on the source organism. Nitrilases are of significant interest in biotechnological applications, including bioremediation and the synthesis of valuable carboxylic acids from nitrile substrates. Additionally, they can be utilized in the pharmaceutical industry for the production of intermediates in drug synthesis. The specificity and efficiency of nitrilases make them valuable tools in organic synthesis and environmental applications, highlighting their importance in both natural processes and industrial uses.

Nitrilase

9024-90-2: Nitrilase, with the CAS number 9024-90-2, is an enzyme that catalyzes the hydrolysis of nitriles to their corresponding carboxylic acids and ammonia. This enzyme is classified under the hydrolases category, specifically those acting on carbon-nitrogen bonds. Nitrilases are typically found in various microorganisms and play a crucial role in nitrogen metabolism, allowing these organisms to utilize nitriles as a nitrogen source. The enzyme operates optimally under specific pH and temperature conditions, which can vary depending on the source organism. Nitrilases are of significant interest in biotechnological applications, including bioremediation and the synthesis of valuable carboxylic acids from nitrile substrates. Additionally, they can be utilized in the pharmaceutical industry for the production of intermediates in drug synthesis. The specificity and efficiency of nitrilases make them valuable tools in organic synthesis and environmental applications, highlighting their importance in both natural processes and industrial uses.

<p>Nitrilase (nitrile aminohydrolase; EC 3.5.5.1) in an enzyme that catalyzes hydrolysis of nitriles to carboxilic acids and ammonia:  R-CN + 2 H2O → R-COO- + NH4+  One unit of nitrilase will yield 1.0 μmol of ammonia per minute under optimal reaction conditions using acrylonitrile as a substrate.</p>

CAS 9024-90-2

Nitrilase

Nitrilase

Ref: 3D-JAA02490