CAS 902457-23-2

(1S,3R,4E,6E,8E,10E,12E,14Z,16E,18S,19R,20R,21S,25R,27R,30R,31R,33S,35R,37S,38R)-3-(4-acetamido-3,5-dihydroxy-6-methyl-tetrahydropyran-2-yl)oxy-19,25,27,30,31,33,35,37-octahydroxy-18,20,21-trimethyl-23-oxo-22,39-dioxabicyclo[33.3.1]nonatriaconta-4,6,8,10,

Description:

The chemical substance with the specified name and CAS number 902457-23-2 is a complex organic molecule characterized by a unique stereochemistry and multiple functional groups. It features a bicyclic structure, which contributes to its rigidity and potential biological activity. The presence of multiple hydroxyl groups indicates that it may exhibit strong hydrogen bonding capabilities, influencing its solubility and reactivity. The acetamido group suggests potential interactions with biological systems, possibly enhancing its pharmacological properties. Additionally, the molecule's configuration includes several double bonds and stereocenters, which may play a crucial role in its interaction with biological targets, such as enzymes or receptors. The intricate arrangement of substituents, including methyl and oxo groups, further suggests that this compound could be of interest in medicinal chemistry or as a natural product. Overall, the complexity of its structure implies that it may possess unique physical and chemical properties, making it a candidate for further research in various scientific fields, including biochemistry and pharmacology.

Formula: C₄₉H₇₅NO₁₈

InChI: InChI=1/C49H75NO18/c1-28-18-16-14-12-10-8-6-7-9-11-13-15-17-19-36(67-48-46(61)43(50-32(5)51)45(60)31(4)66-48)25-40-42(47(62)63)39(57)27-49(64,68-40)26-35(54)23-38(56)37(55)21-20-33(52)22-34(53)24-41(58)65-30(3)29(2)44(28)59/h6-19,28-31,33-40,42-46,48,52-57,59-61,64H,20-27H2,1-5H3,(H,50,51)(H,62,63)/b7-6+,10-8+,11-9+,14-12-,15-13+,18-16+,19-17+/t28-,29-,30-,31?,33+,34+,35-,36-,37+,38+,39-,40-,42+,43?,44+,45?,46?,48?,49+/m0/s1

N-Acetyl amphotericin B

CAS: 902457-23-2

Molecular weight: 966.12

Ref: 7W-GA1972

N-Acetylamphotericin B

CAS: 902457-23-2

N-Acetylamphotericin B is a derivative of the well-known antifungal agent Amphotericin B, which is derived from the bacterium *Streptomyces nodosus*. This compound is an acetylated version of Amphotericin B, designed to improve certain pharmacokinetic properties. It operates by binding to ergosterol, a key component of fungal cell membranes, leading to the formation of pores that disrupt membrane integrity, causing cell death. The acetylation is intended to reduce the compound's cytotoxicity and improve its solubility in aqueous solutions, potentially allowing for enhanced therapeutic applications.

Formula: C₄₉H₇₅NO₁₈

Purity: (%) Min. 75%

Color and Shape: Yellow To Brown Solid

Molecular weight: 966.12 g/mol

Ref: 3D-AA34809