CAS 9026-30-6
:Poly(A) polymerase
Description:
Poly(A) polymerase, with the CAS number 9026-30-6, is an enzyme that plays a crucial role in the post-transcriptional modification of RNA. This enzyme catalyzes the addition of adenine nucleotides to the 3' end of a nascent RNA molecule, forming a poly(A) tail, which is essential for RNA stability, nuclear export, and translation efficiency. Poly(A) polymerase is typically found in eukaryotic cells and is involved in the maturation of messenger RNA (mRNA). The enzyme's activity is influenced by various factors, including the presence of specific cofactors and the cellular environment. It is characterized by its ability to recognize RNA substrates and its dependence on ATP as a substrate for the polymerization process. Additionally, poly(A) polymerase is subject to regulation by various signaling pathways, which can affect gene expression and cellular responses. Its study is significant in understanding RNA biology and has implications in fields such as molecular biology, genetics, and therapeutic development.
Formula:Unspecified
Synonyms:- Polyadenylate nucleotidyltransferase
- Poly(A) polymerase
- Nucleotidyltransferase, polyadenylate
- E.C. 2.7.7.19
- Polyadenylic polymerase
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Poly(A) polymerase
CAS:<p>Poly(A) polymerase enzymatically adds a polyadenosine tail of 20-200 adenine bases to the 3' end of RNA, a process that involves integrating ATP as AMP.</p>Purity:98%Color and Shape:Solid
