CAS 9027-60-5
:N-Acetylneuraminate lyase
Description:
N-Acetylneuraminate lyase, also known as sialate lyase, is an enzyme that catalyzes the cleavage of N-acetylneuraminic acid (a sialic acid) into pyruvate and N-acetylmannosamine. This enzyme plays a crucial role in the metabolism of sialic acids, which are important components of glycoproteins and glycolipids on cell surfaces, influencing cell-cell interactions and signaling. N-Acetylneuraminate lyase is typically found in various bacterial species and is involved in the degradation of sialic acids, contributing to the utilization of these compounds as carbon sources. The enzyme operates through a lyase mechanism, which involves the breaking of chemical bonds without the addition of water, distinguishing it from hydrolases. Its activity can be influenced by factors such as pH and temperature, and it may require specific cofactors for optimal function. The study of this enzyme has implications in understanding bacterial pathogenesis and the development of therapeutic strategies targeting sialic acid metabolism.
Formula:Unspecified
Synonyms:- Acetylneuraminate pyruvate-lyase
- Acylneuraminate pyruvate-lyase
- E.C. 4.1.3.3
- Ec 4.1.3.3
- Lyase, acetylneuraminate
- N-Acetylneuraminate aldolase
- N-Acetylneuraminate lyase
- N-Acetylneuraminate lyases
- N-Acetylneuraminate pyruvatelyase
- N-Acetylneuraminic acid lyase
- N-Acetylneuraminic aldolase
- N-Acetylneuraminic lyase
- N-Acetylneuraminic lyases
- N-Acylneuraminate aldolase
- N-Acylneuraminate lyase
- N-Acylneuraminic acid aldolase
- N-Acylneuraminic aldolase
- N-Acylneuraminic lyase
- Neuraminate aldolase
- Neuraminic acid aldolase
- Neuraminic aldolase
- Sialate lyase
- Sialate pyruvate-lyase
- Sialic acid aldolase
- Sialic acid lyase
- Sialic aldolase
- See more synonyms
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Found 3 products.
Sialic acid aldolase - crystalline
CAS:<p>Sialic acid aldolase - crystalline is a purified enzyme product, which is typically derived from microbial sources, such as certain bacteria, that have evolved to metabolize sialic acids. This enzyme catalyzes a reversible aldol reaction between sialic acid and pyruvate, facilitating the cleavage or formation of sialic acid from N-acetylmannosamine and pyruvate. By breaking the carbon-carbon bond in sialic acid, sialic acid aldolase plays a critical role in the degradation and biosynthesis pathways of sialic acid, which are key factors in numerous biological processes.</p>Color and Shape:PowderSialic acid aldolase - Aqueous solution
CAS:<p>Sialic acid aldolase - Aqueous solution is an enzyme preparation used extensively in biochemical and biotechnological applications. It is derived from microbial sources, where it is expressed and purified to high levels for research purposes. Sialic acid aldolase acts by catalyzing the reversible aldol reaction between N-acetylneuraminic acid (sialic acid) and pyruvate, facilitating the cleavage or synthesis of sialic acid.</p>Color and Shape:Powder
