Citrate synthase is an enzyme that plays a crucial role in the citric acid cycle (Krebs cycle), which is essential for cellular respiration and energy production in aerobic organisms. It catalyzes the condensation of acetyl-CoA and oxaloacetate to form citrate, a key intermediate in metabolic pathways. The enzyme is typically found in the mitochondria of eukaryotic cells and is vital for the regulation of energy metabolism. Citrate synthase is characterized by its specificity for its substrates and its dependence on the presence of certain cofactors, such as magnesium ions, which are necessary for its activity. The enzyme's activity can be influenced by various factors, including pH, temperature, and the concentration of its substrates and products. Additionally, citrate synthase is subject to allosteric regulation, allowing it to respond to the energy needs of the cell. Its CAS number, 9027-96-7, is a unique identifier used to reference this specific enzyme in chemical databases. Overall, citrate synthase is integral to metabolic processes and energy homeostasis in living organisms.

Citrate synthase

9027-96-7: Citrate synthase is an enzyme that plays a crucial role in the citric acid cycle (Krebs cycle), which is essential for cellular respiration and energy production in aerobic organisms. It catalyzes the condensation of acetyl-CoA and oxaloacetate to form citrate, a key intermediate in metabolic pathways. The enzyme is typically found in the mitochondria of eukaryotic cells and is vital for the regulation of energy metabolism. Citrate synthase is characterized by its specificity for its substrates and its dependence on the presence of certain cofactors, such as magnesium ions, which are necessary for its activity. The enzyme's activity can be influenced by various factors, including pH, temperature, and the concentration of its substrates and products. Additionally, citrate synthase is subject to allosteric regulation, allowing it to respond to the energy needs of the cell. Its CAS number, 9027-96-7, is a unique identifier used to reference this specific enzyme in chemical databases. Overall, citrate synthase is integral to metabolic processes and energy homeostasis in living organisms.

<p>Citrate synthase (E.C. 2.3.3.1) is an enzyme that catalyzes the following reaction: acetyl-CoA + oxaloacetate + H2O → citrate + CoA-SHOne unit of citrate synthase will form 1.0 μmole of citrate from acetyl-CoA and oxalacetate per min at pH 8.0 and 37 °C.Origin is porcine heart.Molecular weight ~ 49kDa (monomer) and  ~ 98kDa (dimer)</p>

CAS 9027-96-7

Citrate synthase

Citrate synthase

Ref: 3D-JAA02796