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CAS 9028-38-0

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3-Hydroxybutyrate dehydrogenase

Description:
3-Hydroxybutyrate dehydrogenase (3-HBDH) is an enzyme that plays a crucial role in the metabolism of ketone bodies, particularly in the conversion of acetoacetate to 3-hydroxybutyrate. This enzyme is primarily found in the liver and is involved in the regulation of energy production, especially during periods of fasting or low carbohydrate intake when ketogenesis occurs. The enzyme catalyzes the reversible reaction that interconverts these two compounds, utilizing NADH as a cofactor. 3-HBDH is important in maintaining the balance of ketone bodies in the bloodstream, which can serve as an alternative energy source for tissues, particularly the brain, during prolonged fasting or carbohydrate restriction. The enzyme's activity can be influenced by various factors, including hormonal regulation and the availability of substrates. Its study is significant in understanding metabolic disorders, such as diabetes and conditions related to altered energy metabolism. The CAS number 9028-38-0 identifies this enzyme in chemical databases, facilitating research and application in biochemistry and clinical studies.
Formula:NULL
Synonyms:
  • 3-<span class="text-smallcaps">D</span>-Hydroxybutyrate dehydrogenase
  • 3-D-Hydroxybutyrate dehydrogenase
  • 3-D-Hydroxybutyrate dehydrogenases
  • 3-Hydroxybutanoate dehydrogenase
  • 3-Hydroxybutanoate dehydrogenases
  • 3-Hydroxybutyrate dehydrogenase
  • 3-Hydroxybutyrate dehydrogenases
  • <span class="text-smallcaps">D</span>-(-)-3-Hydroxybutyrate dehydrogenase
  • <span class="text-smallcaps">D</span>-(-)-β-Hydroxybutyrate dehydrogenase
  • D-(-)-3-Hydroxybutyrate dehydrogenase
  • See more synonyms
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