Nicotinamide phosphoribosyltransferase (NAMPT) is an enzyme that plays a crucial role in the biosynthesis of nicotinamide adenine dinucleotide (NAD+), a vital coenzyme involved in various metabolic processes. It catalyzes the transfer of a phosphoribosyl group from phosphoribosyl pyrophosphate (PRPP) to nicotinamide, producing nicotinamide mononucleotide (NMN). This enzyme is significant in cellular energy metabolism, DNA repair, and the regulation of cellular stress responses. NAMPT is found in various tissues and is implicated in several physiological processes, including aging and inflammation. Its activity can be influenced by factors such as nutrient availability and cellular stress, making it a potential target for therapeutic interventions in metabolic disorders and age-related diseases. The CAS number 9030-27-7 identifies this enzyme in chemical databases, facilitating research and development in biochemistry and pharmacology. Overall, NAMPT is essential for maintaining NAD+ levels, which are critical for cellular function and overall health.

nicotinamide phosphoribosyltransferase

9030-27-7: Nicotinamide phosphoribosyltransferase (NAMPT) is an enzyme that plays a crucial role in the biosynthesis of nicotinamide adenine dinucleotide (NAD+), a vital coenzyme involved in various metabolic processes. It catalyzes the transfer of a phosphoribosyl group from phosphoribosyl pyrophosphate (PRPP) to nicotinamide, producing nicotinamide mononucleotide (NMN). This enzyme is significant in cellular energy metabolism, DNA repair, and the regulation of cellular stress responses. NAMPT is found in various tissues and is implicated in several physiological processes, including aging and inflammation. Its activity can be influenced by factors such as nutrient availability and cellular stress, making it a potential target for therapeutic interventions in metabolic disorders and age-related diseases. The CAS number 9030-27-7 identifies this enzyme in chemical databases, facilitating research and development in biochemistry and pharmacology. Overall, NAMPT is essential for maintaining NAD+ levels, which are critical for cellular function and overall health.

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CAS 9030-27-7

nicotinamide phosphoribosyltransferase

Nicotinamide phosphoribosyltransferase, liquid

Ref: 3D-ETS027.7