CAS 90332-64-2
:10-Deacetyl-7-xylosyltaxol B
Description:
10-Deacetyl-7-xylosyltaxol B, identified by its CAS number 90332-64-2, is a chemical compound that belongs to the class of taxanes, which are known for their complex polycyclic structures and significant biological activity. This substance is characterized by its unique molecular framework, which includes a taxane core modified by the presence of a xylosyl group and the absence of an acetyl group at the 10-position. The compound exhibits notable pharmacological properties, particularly in the context of cancer treatment, as taxanes are often utilized for their ability to inhibit cell division by stabilizing microtubules. Additionally, the presence of the xylosyl moiety may influence its solubility and bioavailability, potentially affecting its therapeutic efficacy. As with many natural products derived from plant sources, the compound may also exhibit a range of biological activities beyond its antitumor effects, making it a subject of interest for further research in medicinal chemistry and pharmacology.
Formula:C48H59NO17
InChI:InChI=1S/C48H59NO17/c1-8-23(2)41(57)49-33(26-15-11-9-12-16-26)36(54)43(59)63-29-20-48(60)40(65-42(58)27-17-13-10-14-18-27)38-46(7,39(56)35(53)32(24(29)3)45(48,5)6)30(19-31-47(38,22-62-31)66-25(4)50)64-44-37(55)34(52)28(51)21-61-44/h8-18,28-31,33-38,40,44,51-55,60H,19-22H2,1-7H3,(H,49,57)/b23-8+/t28-,29+,30+,31-,33+,34+,35-,36-,37-,38+,40+,44+,46-,47+,48-/m1/s1
InChI key:InChIKey=YAOWLIDDDUBAEI-ZVZSAYPQSA-N
SMILES:O(C(C)=O)[C@]12[C@@]3([C@@](C)([C@@H](O[C@H]4[C@H](O)[C@@H](O)[C@H](O)CO4)C[C@]1(OC2)[H])C(=O)[C@H](O)C=5C(C)(C)[C@](O)([C@H]3OC(=O)C6=CC=CC=C6)C[C@H](OC([C@@H]([C@@H](NC(/C(=C/C)/C)=O)C7=CC=CC=C7)O)=O)C5C)[H]
Synonyms:- 7,11-Methano-1H-cyclodeca[3,4]benz[1,2-b]oxete, benzenepropanoic acid deriv.
- 10-Deacetylcephalomannine 7-xyloside
- Benzenepropanoic acid, α-hydroxy-β-[(2-methyl-1-oxo-2-butenyl)amino]-, 12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-6,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-4-(β-D-xylopyranosyloxy)-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, [2aR-[2aα,4β,4aβ,6β,9a[αR*,βS*(E)],11α,12α,12aα,12bα]]-
- Benzenepropanoic acid, α-hydroxy-β-[[(2E)-2-methyl-1-oxo-2-buten-1-yl]amino]-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-6,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-4-(β-D-xylopyranosyloxy)-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester
- Benzenepropanoic acid, α-hydroxy-β-[[(2E)-2-methyl-1-oxo-2-butenyl]amino]-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-6,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-4-(β-D-xylopyranosyloxy)-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)-
- 7-Xylosyl-10-deacetylcephalomannine
- 10-Deacetyl-7-xylosyltaxol B
- Benzenepropanoic acid, α-hydroxy-β-[[(2E)-2-methyl-1-oxo-2-buten-1-yl]amino]-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-6,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-4-(β-D-xylopyranosyloxy)-7,11-methano-1H-cyclodeca[3,4]benz[1,2...
- 7-Xylosyl-10-deacetyltaxol B
- DEACETYL-7-XYLOSYLCEPHALOMANNINE, 10-(RG)
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Found 4 products.
7-Xylosyl-10-deacetyltaxol B
CAS:7-Xylosyl-10-deacetyltaxol B (7-xylosyl-10-Deacetylpaclitaxel B) is a paclitaxel derivative with antitumour activity that is used in the synthesis of paclitaxelFormula:C48H59NO17Purity:98%Color and Shape:SolidMolecular weight:921.987-Xylosyl-10-deacetyltaxol B
CAS:<p>7-Xylosyl-10-deacetyltaxol B is a natural product derivative, which is a taxoid compound commonly isolated from yew tree species such as Taxus brevifolia. This derivative is structurally adapted from the well-known chemotherapeutic agent paclitaxel. The source, primarily the bark and needles of yew plants, provides a rich repository of taxanes, which are crucial for their cytotoxic properties against cancer cells.</p>Formula:C48H59NO17Purity:Min. 95%Molecular weight:922 g/mol



