CAS 90332-65-3

7-Xylosyl-10-deacetyltaxol C

Description:

7-Xylosyl-10-deacetyltaxol C, with the CAS number 90332-65-3, is a chemical compound that belongs to the taxane family, which is known for its role in cancer treatment due to its ability to inhibit cell division. This compound features a xylosyl group, which is a sugar moiety, attached to the taxane structure, enhancing its solubility and potentially its biological activity. The presence of the deacetylated form indicates that it lacks an acetyl group, which may influence its pharmacokinetics and therapeutic efficacy. Taxanes, including derivatives like this one, typically exhibit significant antitumor properties by stabilizing microtubules and preventing their depolymerization, thus disrupting the normal mitotic process in cancer cells. The specific characteristics, such as its solubility, stability, and biological activity, would depend on its molecular structure and the functional groups present. Further studies would be necessary to fully elucidate its pharmacological profile and potential applications in oncology.

Formula: C₄₉H₆₃NO₁₇

InChI: InChI=1S/C49H63NO17/c1-7-8-11-20-33(53)50-35(27-16-12-9-13-17-27)38(56)44(60)64-30-22-49(61)42(66-43(59)28-18-14-10-15-19-28)40-47(6,41(58)37(55)34(25(30)2)46(49,4)5)31(21-32-48(40,24-63-32)67-26(3)51)65-45-39(57)36(54)29(52)23-62-45/h9-10,12-19,29-32,35-40,42,45,52,54-57,61H,7-8,11,20-24H2,1-6H3,(H,50,53)/t29-,30+,31+,32-,35+,36+,37-,38-,39-,40+,42+,45+,47-,48+,49-/m1/s1

InChI key: InChIKey=XGWGQEYABFGJID-UVDBIDMBSA-N

SMILES: O(C(C)=O)[C@]12[C@@]3([C@@](C)([C@@H](O[C@H]4[C@H](O)[C@@H](O)[C@H](O)CO4)C[C@]1(OC2)[H])C(=O)[C@H](O)C=5C(C)(C)[C@](O)([C@H]3OC(=O)C6=CC=CC=C6)C[C@H](OC([C@@H]([C@@H](NC(CCCCC)=O)C7=CC=CC=C7)O)=O)C5C)[H]

Synonyms:

• 10-Deacetyl-7-xylosyltaxol C
• 10-Deacetylpaclitaxel C 7-xyloside
• 10-Deacetyltaxol C 7-xyloside
• 7,11-Methano-1H-cyclodeca[3,4]benz[1,2-b]oxete, benzenepropanoic acid deriv.
• 7-(b-Xylosyl)-10-deacetyltaxol C
• 7-Xylosyl-10-deacetyltaxol C
• Benzenepropanoic acid, α-hydroxy-β-[(1-oxohexyl)amino]-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-6,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-4-(β-<span class="text-smallcaps">D</span>-xylopyranosyloxy)-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)-
• Benzenepropanoic acid, α-hydroxy-β-[(1-oxohexyl)amino]-, 12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-6,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-4-(β-<span class="text-smallcaps">D</span>-xylopyranosyloxy)-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, [2aR-[2aα,4β,4aβ,6β,9α(αR*,βS*),11α,12α,12aα,12bα]]-
• Benzenepropanoicacid, a-hydroxy-b-[(1-oxohexyl)amino]-,12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-6,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-4-(b-D-xylopyranosyloxy)-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-ylester, [2aR-[2aa,4b,4ab,6b,9a(aR*,bS*),11a,12a,12aa,12ba]]-
• Benzenepropanoic acid, α-hydroxy-β-[(1-oxohexyl)amino]-, 12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-6,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-4-(β-D-xylopyranosyloxy)-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, [2aR-[2aα,4β,4aβ,6β,9α(αR*,βS*),11α,12α,12aα,12bα]]-
• Benzenepropanoic acid, α-hydroxy-β-[(1-oxohexyl)amino]-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-6,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-4-(β-D-xylopyranosyloxy)-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)-

7-Xylosyl-10-deacetyltaxol C

CAS: 90332-65-3

7-Xylosyl-10-deacetyltaxol C is a natural product from Taxus wallichiana Zucc.

Formula: C₄₉H₆₃NO₁₇

Purity: 98%

Color and Shape: Solid

Molecular weight: 938.033

Ref: TM-TN1336

7-Xylosyl-10-deacetyltaxol C

CAS: 90332-65-3

Formula: C₄₉H₆₃NO₁₇

Purity: 95%~99%

Molecular weight: 938.033

Ref: BP-SBP03706

Deacetyl-7-xylosyltaxol C

CAS: 90332-65-3

Deacetyl-7-xylosyltaxol C is a complex taxol derivative, which is a naturally occurring compound obtained from the bark of the Pacific yew tree, Taxus brevifolia, and other related species. This unique derivative is structurally modified by the removal of an acetyl group and the addition of a xylose moiety, which is characteristic of its taxonomy.

Formula: C₄₉H₆₃NO₁₇

Purity: Min. 95%

Molecular weight: 938 g/mol

Ref: 3D-QDA33265