Glycogen phosphorylase is an enzyme that plays a crucial role in carbohydrate metabolism, specifically in the breakdown of glycogen into glucose-1-phosphate. It catalyzes the phosphorolytic cleavage of glycogen, facilitating the mobilization of glucose for energy production, particularly during periods of fasting or intense exercise. This enzyme is found in various tissues, with significant concentrations in muscle and liver cells. Glycogen phosphorylase exists in two forms: phosphorylase a (active) and phosphorylase b (inactive), which are regulated by allosteric effectors and covalent modifications, such as phosphorylation. The activity of glycogen phosphorylase is influenced by factors like energy status, hormonal signals (e.g., adrenaline and glucagon), and the availability of substrates. Dysregulation of this enzyme can lead to metabolic disorders, including glycogen storage diseases. Its CAS number, 9035-74-9, identifies it in chemical databases, facilitating research and application in biochemistry and pharmacology. Overall, glycogen phosphorylase is essential for maintaining glucose homeostasis and energy balance in the body.

Glycogen phosphorylase

9035-74-9: Glycogen phosphorylase is an enzyme that plays a crucial role in carbohydrate metabolism, specifically in the breakdown of glycogen into glucose-1-phosphate. It catalyzes the phosphorolytic cleavage of glycogen, facilitating the mobilization of glucose for energy production, particularly during periods of fasting or intense exercise. This enzyme is found in various tissues, with significant concentrations in muscle and liver cells. Glycogen phosphorylase exists in two forms: phosphorylase a (active) and phosphorylase b (inactive), which are regulated by allosteric effectors and covalent modifications, such as phosphorylation. The activity of glycogen phosphorylase is influenced by factors like energy status, hormonal signals (e.g., adrenaline and glucagon), and the availability of substrates. Dysregulation of this enzyme can lead to metabolic disorders, including glycogen storage diseases. Its CAS number, 9035-74-9, identifies it in chemical databases, facilitating research and application in biochemistry and pharmacology. Overall, glycogen phosphorylase is essential for maintaining glucose homeostasis and energy balance in the body.

<p>Phosphorylase is an enzyme that plays a crucial role in carbohydrate metabolism, primarily sourced from various biological organisms, including humans, plants, and bacteria. Its mode of action involves catalyzing the breakdown of glycogen into glucose-1-phosphate by adding an inorganic phosphate group. This process is critical in regulating energy release and storage within cells.</p>

CAS 9035-74-9

Glycogen phosphorylase

Phosphorylase

Ref: 3D-FP158108