Lucatumumab, identified by the CAS number 903512-50-5, is a monoclonal antibody that primarily targets the CD37 antigen, which is expressed on the surface of certain immune cells and various hematological malignancies. This therapeutic agent is designed to modulate the immune response and has been investigated for its potential in treating conditions such as non-Hodgkin lymphoma and chronic lymphocytic leukemia. Lucatumumab functions by binding to CD37, leading to the activation of immune effector mechanisms, including antibody-dependent cellular cytotoxicity (ADCC). Its structure is characterized by the typical Y-shaped configuration of antibodies, consisting of two heavy chains and two light chains, which facilitate its specific binding to the target antigen. The development of lucatumumab reflects the growing trend in biopharmaceuticals to utilize monoclonal antibodies for targeted therapy, aiming to improve treatment efficacy while minimizing off-target effects. As with many monoclonal antibodies, its pharmacokinetics, safety profile, and therapeutic efficacy are subjects of ongoing clinical research.

Lucatumumab

903512-50-5: Lucatumumab, identified by the CAS number 903512-50-5, is a monoclonal antibody that primarily targets the CD37 antigen, which is expressed on the surface of certain immune cells and various hematological malignancies. This therapeutic agent is designed to modulate the immune response and has been investigated for its potential in treating conditions such as non-Hodgkin lymphoma and chronic lymphocytic leukemia. Lucatumumab functions by binding to CD37, leading to the activation of immune effector mechanisms, including antibody-dependent cellular cytotoxicity (ADCC). Its structure is characterized by the typical Y-shaped configuration of antibodies, consisting of two heavy chains and two light chains, which facilitate its specific binding to the target antigen. The development of lucatumumab reflects the growing trend in biopharmaceuticals to utilize monoclonal antibodies for targeted therapy, aiming to improve treatment efficacy while minimizing off-target effects. As with many monoclonal antibodies, its pharmacokinetics, safety profile, and therapeutic efficacy are subjects of ongoing clinical research.

<p>Lucatumumab (HCD122) is a fully human anti-CD40 monoclonal antibody with anti-tumor activity for the study of multiple myeloma.</p>

<p>Anti-Human CD40 Monoclonal Antibody</p>

CAS 903512-50-5

Lucatumumab

Lucatumumab

Ref: TM-T76729

Lucatumumab

Ref: 3D-CLA1143