CAS: 903565-83-3 - Tofogliflozin

Formula: C₂₂H₂₆O₆

InChI: InChI=1S/C22H26O6/c1-2-13-3-5-14(6-4-13)9-15-7-8-16-12-27-22(17(16)10-15)21(26)20(25)19(24)18(11-23)28-22/h3-8,10,18-21,23-26H,2,9,11-12H2,1H3/t18-,19-,20+,21-,22+/m1/s1

InChI key: InChIKey=VWVKUNOPTJGDOB-BDHVOXNPSA-N

SMILES: OCC1OC2(OCC3=CC=C(C=C32)CC4=CC=C(C=C4)CC)C(O)C(O)C1O

Synonyms:

• (1S,3'R,4'S,5'S,6'R)-6-[(4-Ethylphenyl)methyl]-3',4',5',6'-tetrahydro-6'-(hydroxymethyl)-spiro[isobenzofuran-1(3H),2'-[2H]pyran]-3',4',5'-triol
• (1S,3′R,4′S,5′S,6′R)-6-[(4-Ethylphenyl)methyl]-3′,4′,5′,6′-tetrahydro-6′-(hydroxymethyl)spiro[isobenzofuran-1(3H),2′-[2H]pyran]-3′,4′,5′-triol
• Csg 452
• R-7201
• Spiro[isobenzofuran-1(3H),2′-[2H]pyran]-3′,4′,5′-triol, 6-[(4-ethylphenyl)methyl]-3′,4′,5′,6′-tetrahydro-6′-(hydroxymethyl)-, (1S,3′R,4′S,5′S,6′R)-
• Tofogliflozin

Tofogliflozin

CAS: 903565-83-3

• Formula: C₂₂H₂₆O₆
• Color and Shape: Solid
• Molecular weight: 386.4382

Tofogliflozin

CAS: 903565-83-3

Tofogliflozin specifically inhibits SGLT2; IC50s are 2.9 nM (human), 14.9 nM (rat), 6.4 nM (mouse).

• Formula: C₂₂H₂₆O₆
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 386.444

Tofogliflozin

CAS: 903565-83-3

• Formula: C₂₂H₂₆O₆
• Molecular weight: 386.45

Tofogliflozin

CAS: 903565-83-3

Applications A novel, potent, and highly selective SGLT2 inhibitor that has been shown to improve …

• Formula: C₂₂H₂₆O₆
• Color and Shape: Neat
• Molecular weight: 386.44

Tofogliflozin

CAS: 903565-83-3

Tofogliflozin is a glucose-lowering drug that acts as an inhibitor of sodium-glucose transport (SGLT2) in …

• Formula: C₂₂H₂₆O₆
• Purity: Min. 95%
• Color and Shape: White Powder
• Molecular weight: 386.44 g/mol