CAS 9041-93-4
:Bleomycin sulfate
Description:
Bleomycin sulfate is a glycopeptide antibiotic derived from the bacterium Streptomyces verticillus. It is primarily used in cancer chemotherapy, particularly for treating testicular cancer, Hodgkin's lymphoma, and certain types of squamous cell carcinomas. The compound exhibits a unique mechanism of action by inducing DNA strand breaks, which leads to inhibition of DNA synthesis and ultimately triggers apoptosis in cancer cells. Bleomycin is known for its relatively low myelosuppressive effects compared to other chemotherapeutic agents, making it a valuable option in combination therapies. However, it can cause dose-dependent toxicities, particularly pulmonary toxicity, which necessitates careful monitoring during treatment. The sulfate form enhances its solubility and stability, facilitating its use in clinical settings. Bleomycin is typically administered via injection, and its efficacy can be influenced by factors such as the tumor type and the presence of specific resistance mechanisms in cancer cells. Overall, Bleomycin sulfate remains an important agent in oncology, with ongoing research exploring its potential in various therapeutic contexts.
Formula:C110H168N34O46S7
InChI:InChI=1/C52H77N13O19S3/c1-7-11-54-18-32-56-13-9-26(62-32)45(75)65-35(41(27-16-55-22-60-27)82-51-43(39(72)37(70)29(19-66)81-51)83-50-40(73)42(84-52(53)79)38(71)30(20-67)80-50)48(78)61-24(3)36(69)23(2)44(74)64-34(25(4)68)47(77)58-14-10-33-63-28(21-85-33)49-59-17-31(86-49)46(76)57-12-8-15-87(5)6/h9,13,16-17,21-25,29-30,34-43,50-51,54,66-73H,7-8,10-12,14-15,18-20H2,1-6H3,(H7-,53,55,57,58,60,61,64,65,74,75,76,77,78,79)/p+1/t23-,24+,25?,29+,30+,34?,35+,36-,37+,38-,39+,40-,41+,42+,43-,50-,51+/m0/s1
Synonyms:- 3-[[2-[2-[2-[[2-[[(2S,3S,4R)-4-[[(2R,3S)-3-[(2S,3S,4R,5S,6R)-3-[(2S,3S,4R,5S,6R)-4-carbamoyloxy-3,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-3-(1H-imidazol-4-yl)-2-[[2-(propylaminomethyl)pyrimidine-4-carbonyl]amino]propanoyl]amino]-3-hydroxy-2-methyl-pentanoyl]amino]-3-hydroxy-butanoyl]amino]ethyl]thiazol-4-yl]thiazole-5-carbonyl]amino]propyl-dimethyl-sulfonium
- Blenoxane
- Bleomycin Sulfate From Streptomyces Verticillus
- Bleomycin, sulfate (salt)
- Bleomycine Sulfate
- Blexane
- Bleomycin sulfate
- BLEOMYCIN SULFATE, STREPTOMYCES VERTICILLUS
- BLEOMYCIN SULFATE FROM STREPTOMYCES VERTICILLUS 0 TO 5 °C
- BLEOMYCIN SULFATE FROM STREPTOMYCES VERT ICILLUS, LYOPH.
- Blenoxane, Bleo, Blexane
- BLEO
- 3-[[2-[2-[2-[2-[4-[2-[6-Amino-2-[1-(2-amino-2-carbamoyl-ethyl)amino-2-carbamoyl-ethyl]-5-methyl-pyrimidin-4-yl]carbonylamino-3-[3-[4-carbamoyloxy-3,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-3-(3H-imidazol-4-yl)propanoyl]amino-3-hydroxy-2-methyl-pentanoyl]amino-3-hydroxy-butanoyl]aminoethyl]-1,3-thiazol-4-yl]-1,3-thiazol-4-yl]carbonylamino]propyl-dimethyl-sulfonium hydrogen sulfate
- BLEMOYCIN SULFATE
- BLEOMYCIN SULFATE CELL CULTURE TESTED
- BLEOMYCIN SULPHATE
- Bleomycin Sulfate, Blenoxane
- Blenmycins
- Bleomycin Sulfate (A mixture of bleomycin sulfate salts)
- BLEOMYCIN SULFATE, BPC
- NSC-125066
- See more synonyms
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Found 15 products.
Bleomycin Sulfate (mixture)
CAS:Purity:>85.0%(HPLC)Color and Shape:White to Light yellow powder to crystalBleomycin sulfate
CAS:<p>Bleomycin sulfate, 9041-93-4, is a glycopeptide antibiotic isolated from Streptomyces verticillus which has antineoplastic properties. Learn more at Thermo Fisher Scientific.</p>Formula:C55H85N17O25S4Molecular weight:1512.62Bleomycin sulfate, Cell Culture Grade
CAS:<p>This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.</p>Formula:C55H85N17O25S4Color and Shape:White to pale cream to pale yellow, PowderMolecular weight:1512.62BLEOMYCIN SULFATE CRS
CAS:<p>BLEOMYCIN SULFATE CRS</p>Formula:C55H84N17O21S3Color and Shape:White. Light Yellow. Powder.Molecular weight:1415.551Bleomycin sulfate
CAS:Bleomycin sulfateFormula:C55H84N17O21S3Color and Shape:WhiteMolecular weight:1415.551SECOND INTERNATIONAL STANDARD FOR BLEOMYCIN COMPLEX A2/B2
CAS:<p>SECOND INTERNATIONAL STANDARD FOR BLEOMYCIN COMPLEX A2/B2</p>Formula:C55H84N17O21S3Molecular weight:1415.551Bleomycin Sulfate
CAS:<p>Antibiotics nesoi</p>Formula:NA(Mixture)Color and Shape:Cream PowderMolecular weight:1415.551Ref: IN-DA003913
5gTo inquire10gTo inquire5mg79.00€10mg109.00€25mg122.00€50mg174.00€100mg318.00€250mgTo inquireBleomycin sulfate, low endotoxin
CAS:Formula:C55H85N17O25S4Purity:≥ 90% (A2+B2)Color and Shape:White to off-white crystalline powderMolecular weight:1512.62Bleomycin sulphate
CAS:<p>Bleomycin sulphate</p>Formula:C55H85N17O25S4Purity:By hplc: bleomycin a2: 68.19% (Typical Value in Batch COA)Color and Shape: white powderMolecular weight:2,927.17g/molBleomycin sulfate
CAS:Formula:C55H85N17O25S4Purity:≥ 90% (A2+B2, anhydrous basis)Color and Shape:White to off-white crystalline powderMolecular weight:1512.62Bleomycin Sulfate
CAS:Formula:C55H84N20O21S2·H2SO4C55H84N17O21S3·H2SO4Color and Shape:White To Off-White SolidMolecular weight:1415.55 98.07; 1425.52 98.07Bleomycin Sulfate
CAS:<p>Bleomycin Sulfate (Blenoxane) is a glycopeptide antibiotic, an inhibitor of DNA synthesis.</p>Formula:C55H85N17O25S4Purity:98% - ≥98%Color and Shape:Less Or Yellowish Powder Possible Bluish Color Depending On Copper Content (Ntp 1992)Molecular weight:1523 (average)Bleomycin sulfate - mixture of Bleomycin A2, B2
CAS:<p>Inducer of DNA strand breaks; glycopeptide antibiotic, anti-neoplastic</p>Formula:C55H84N17O21S3·xH2SO4Purity:Min. 77 Area-%Color and Shape:PowderMolecular weight:1,415.56 g/mol
