CAS 90417-38-2

8-Hydroxy-2-methyl-4(3H)-quinazolinone

Description:

8-Hydroxy-2-methyl-4(3H)-quinazolinone, with the CAS number 90417-38-2, is a heterocyclic organic compound characterized by its quinazolinone structure, which features a fused benzene and pyrimidine ring system. This compound typically exhibits a hydroxyl group at the 8-position and a methyl group at the 2-position, contributing to its unique chemical properties. It is known for its potential biological activities, including antimicrobial and anti-inflammatory effects, making it of interest in pharmaceutical research. The presence of the hydroxyl group enhances its solubility in polar solvents and may influence its reactivity and interaction with biological targets. Additionally, the compound may exhibit fluorescence properties, which can be useful in analytical applications. Its stability and reactivity can vary depending on environmental conditions such as pH and temperature. Overall, 8-Hydroxy-2-methyl-4(3H)-quinazolinone represents a significant compound in medicinal chemistry, with ongoing research into its applications and mechanisms of action.

Formula: C₉H₈N₂O₂

InChI: InChI=1S/C9H8N2O2/c1-5-10-8-6(9(13)11-5)3-2-4-7(8)12/h2-4,12H,1H3,(H,10,11,13)

InChI key: InChIKey=YJDAOHJWLUNFLX-UHFFFAOYSA-N

SMILES: O=C1C=2C(NC(C)=N1)=C(O)C=CC2

Synonyms:

• 4(1H)-Quinazolinone, 8-hydroxy-2-methyl-
• 4(3H)-Quinazolinone, 8-hydroxy-2-methyl-
• 8-Hydroxy-2-methyl-4(3H)-quinazolinone
• 8-hydroxy-2-methylquinazolin-4(1H)-one
• NSC 696807
• Nu-1025
• Nu1025

NU1025

CAS: 90417-38-2

Formula: C₉H₈N₂O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 176.1720

Ref: IN-DA003NIF

NU-1025

CAS: 90417-38-2

Formula: C₉H₈N₂O₂

Molecular weight: 176.17

Ref: 7W-GL6752

NU1025

CAS: 90417-38-2

NU1025

Purity: ≥98%

Molecular weight: 176.17g/mol

Ref: 54-BUP13060

Nu1025

CAS: 90417-38-2

Nu1025

Purity: 98%

Molecular weight: 176.17g/mol

Ref: 54-OR1023212

NU1025

CAS: 90417-38-2

NU1025 (NSC-696807) is a potent PARP inhibitor with IC50 of 400 nM.

Formula: C₉H₈N₂O₂

Purity: 99.86%

Color and Shape: Solid

Molecular weight: 176.17

Ref: TM-T6912

8-hydroxy-2-methyl-1,4-dihydroquinazolin-4-one

CAS: 90417-38-2

Purity: 98%

Molecular weight: 176.1750031

Ref: 10-F900378

8-Hydroxy-2-methyl-4(3H)-quinazolinone

Controlled Product

CAS: 90417-38-2

Applications A potent inhibitor of poly (ADP-ribose) polymerase (PARP). Ki and IC50 values are 48 and 400 nM respectively.
References Griffin, R.J., et al.: J. Med. Chem., 41, 5247 (1998), De Soto, J., et al.: Int. J. Biol. Sci., 2, 179 (2006),

Formula: C₉H₈N₂O₂

Color and Shape: Neat

Molecular weight: 176.17

Ref: TR-H948330