Cathepsin B is a cysteine protease enzyme that plays a crucial role in various physiological processes, including protein degradation, antigen processing, and apoptosis. It is primarily found in lysosomes and is involved in the turnover of cellular proteins. The enzyme is characterized by its ability to cleave peptide bonds, particularly those adjacent to basic amino acids, which is essential for its function in cellular metabolism and immune response. Cathepsin B is also implicated in pathological conditions, such as cancer and neurodegenerative diseases, due to its role in tissue remodeling and inflammation. The enzyme is synthesized as an inactive precursor and activated in acidic environments, which is typical for lysosomal enzymes. Its activity can be regulated by various inhibitors, making it a target for therapeutic interventions. The CAS number 9047-22-7 refers to a specific classification for this enzyme, facilitating its identification in chemical databases and research. Overall, Cathepsin B is a vital enzyme with significant implications in both health and disease.

Cathepsin B

9047-22-7: Cathepsin B is a cysteine protease enzyme that plays a crucial role in various physiological processes, including protein degradation, antigen processing, and apoptosis. It is primarily found in lysosomes and is involved in the turnover of cellular proteins. The enzyme is characterized by its ability to cleave peptide bonds, particularly those adjacent to basic amino acids, which is essential for its function in cellular metabolism and immune response. Cathepsin B is also implicated in pathological conditions, such as cancer and neurodegenerative diseases, due to its role in tissue remodeling and inflammation. The enzyme is synthesized as an inactive precursor and activated in acidic environments, which is typical for lysosomal enzymes. Its activity can be regulated by various inhibitors, making it a target for therapeutic interventions. The CAS number 9047-22-7 refers to a specific classification for this enzyme, facilitating its identification in chemical databases and research. Overall, Cathepsin B is a vital enzyme with significant implications in both health and disease.

<p>Cathepsin B, a cysteine protease located within the subcellular endosomes and lysosomal compartments, mediates apoptosis and can be used in cancer research.</p>

<p>Cathepsin B is a lysosomal proteolytic enzyme of the cysteine protease family. It is present in all mammalian cells. It is essential for the intracellular protein turnover.  Cathepsin B may be a useful tool in Alzheimer′s research, as it may have a role in the natural defense against the disease.</p>

CAS 9047-22-7

Cathepsin B

Cathepsin B

Ref: TM-T80052

Cathepsin B from human placenta

Ref: 3D-JAA04722