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CAS 9054-89-1

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Superoxide dismutase

Description:
Superoxide dismutase (SOD) is an essential enzyme that plays a critical role in protecting cells from oxidative stress by catalyzing the dismutation of superoxide radicals into oxygen and hydrogen peroxide. This enzyme is found in various forms across different organisms, including humans, where it exists primarily in three isoforms: cytosolic (Cu/Zn SOD), mitochondrial (Mn SOD), and extracellular (EC SOD). Each isoform has distinct characteristics and metal cofactors, with copper and zinc being present in the cytosolic form, while manganese is found in the mitochondrial variant. SOD is crucial for maintaining cellular health, as it helps mitigate damage caused by reactive oxygen species (ROS), which can lead to cellular aging and various diseases. The enzyme's activity is influenced by factors such as pH, temperature, and the presence of metal ions. Due to its protective role, SOD is of significant interest in biomedical research, particularly in studies related to neurodegenerative diseases, cancer, and aging. Its CAS number, 9054-89-1, is used for identification in chemical databases and regulatory contexts.
Formula:Unspecified
Synonyms:
  • Artolasi
  • Copper-zinc superoxide dismutase
  • Cu,Zn-SOD
  • Cu-Zn superoxide dismutase
  • Cuprein
  • Cytocuprein
  • Czsod
  • Dismutasa, Superoxido
  • Dismutase
  • Dismutase, Superoxid
  • See more synonyms
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