CAS 90566-53-3

Fluticasone

Description:

Fluticasone is a synthetic corticosteroid used primarily for its anti-inflammatory and immunosuppressive properties. It is commonly administered in the treatment of respiratory conditions such as asthma and chronic obstructive pulmonary disease (COPD), as well as for allergic rhinitis and skin disorders. The substance is characterized by its high affinity for glucocorticoid receptors, which allows it to effectively modulate gene expression and inhibit the release of pro-inflammatory mediators. Fluticasone is typically available in various formulations, including inhalers, nasal sprays, and topical creams, enhancing its versatility in clinical applications. Its chemical structure features a fluorinated steroid backbone, contributing to its potency and prolonged action. The compound is generally well-tolerated, although potential side effects may include local irritation or systemic effects with prolonged use. Due to its efficacy and safety profile, fluticasone remains a widely prescribed medication in the management of inflammatory conditions.

Formula: C₂₂H₂₇F₃O₄S

InChI: InChI=1S/C22H27F3O4S/c1-11-6-13-14-8-16(24)15-7-12(26)4-5-19(15,2)21(14,25)17(27)9-20(13,3)22(11,29)18(28)30-10-23/h4-5,7,11,13-14,16-17,27,29H,6,8-10H2,1-3H3/t11-,13+,14+,16+,17+,19+,20+,21+,22+/m1/s1

InChI key: InChIKey=MGNNYOODZCAHBA-GQKYHHCASA-N

SMILES: C[C@@]12[C@]([C@]3([C@@](F)([C@]4(C)C([C@@H](F)C3)=CC(=O)C=C4)[C@@H](O)C1)[H])(C[C@@H](C)[C@@]2(C(SCF)=O)O)[H]

Synonyms:

• Fluticasone
• VR 506
• Androsta-1,4-diene-17-carbothioic acid, 6,9-difluoro-11,17-dihydroxy-16-methyl-3-oxo-, S-(fluoromethyl) ester, (6α,11β,16α,17α)-

Fluticasone

CAS: 90566-53-3

Formula: C₂₂H₂₇F₃O₄S

Color and Shape: White To Off-White Solid

Molecular weight: 444.51

Ref: 4Z-F-0926

Fluticasone

Controlled Product

CAS: 90566-53-3

Formula: C₂₂H₂₇F₃O₄S

Color and Shape: Neat

Molecular weight: 444.51

Ref: TR-F599456

Fluticasone-d3

Controlled Product

CAS: 90566-53-3

Formula: C₂₂D₃H₂₄F₃O₄S

Color and Shape: Neat

Molecular weight: 447.526

Ref: TR-F599457

(6S,9S,10S,11S,13S,14S,16R,17R)-6,9-Difluoro-17-(fluoromethylsulfanylcarbonyl)-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15, 16-octahydrocyclopenta[a]phenanthren-3-one

Controlled Product

CAS: 90566-53-3

Isopropyl (6S,9S,10S,11S,13S,14S,16R,17R)-6,9-difluoro-17-(fluoromethylsulfanylcarbonyl)-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14 ,15,-16-octahydrocyclopenta[a]phenanthren-3-one is an organic compound that is a reagent used in the synthesis of corticosteroids. It has been shown to have bronchodilatory effects in patients with bronchial asthma and can be used as a treatment for asthma symptoms. The mechanism of action of this drug is not yet fully understood. Isopropyl (6S,9S)10S)11S)13S)14R)16R)17R)-6-(fluorometh

Formula: C₂₂H₂₇F₃O₄S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 444.51 g/mol

Ref: 3D-FD64040