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CAS 9059-23-8

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P-hydroxybenzoate hydroxylase from*pseudomonas sp

Description:
P-hydroxybenzoate hydroxylase is an enzyme produced by certain strains of Pseudomonas species, playing a crucial role in the microbial degradation of aromatic compounds. This enzyme catalyzes the hydroxylation of p-hydroxybenzoate to form 3,4-dihydroxybenzoate, utilizing molecular oxygen and reducing equivalents, typically derived from NAD(P)H. The enzyme is characterized by its specificity for p-hydroxybenzoate and its dependence on metal ions, often requiring iron or other cofactors for optimal activity. It exhibits a relatively high turnover rate and is sensitive to environmental conditions such as pH and temperature, which can influence its stability and activity. The enzyme's ability to facilitate the breakdown of aromatic compounds makes it significant in bioremediation processes, where it aids in the detoxification of pollutants. Additionally, the study of P-hydroxybenzoate hydroxylase contributes to our understanding of microbial metabolism and the enzymatic mechanisms involved in the transformation of complex organic molecules.
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