CAS 906008-94-4

N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-methylpropanamide

Description:

N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-methylpropanamide, with the CAS number 906008-94-4, is a synthetic organic compound characterized by its complex molecular structure, which includes a cyano group, trifluoromethyl group, and a sulfonamide moiety. This compound is typically a solid at room temperature and exhibits high stability due to the presence of strong covalent bonds. Its molecular structure suggests potential applications in pharmaceuticals, particularly in the development of targeted therapies, owing to the presence of functional groups that can interact with biological targets. The trifluoromethyl and fluorophenyl groups may enhance lipophilicity and bioavailability, making it a candidate for drug development. Additionally, the sulfonamide group is known for its role in various biological activities, including antimicrobial properties. The compound's solubility and reactivity can vary based on the solvent and conditions, which are important considerations for its practical applications in research and industry.

Formula: C₁₈H₁₄F₄N₂O₃S

InChI: InChI=1/C18H14F4N2O3S/c1-11(10-28(26,27)15-6-3-13(19)4-7-15)17(25)24-14-5-2-12(9-23)16(8-14)18(20,21)22/h2-8,11H,10H2,1H3,(H,24,25)

SMILES: CC(CS(=O)(=O)c1ccc(cc1)F)C(=Nc1ccc(C#N)c(c1)C(F)(F)F)O

Deoxybicalutamide (N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-(4-fluorophenylsulfonyl)-2-methylpropanamide)

CAS: 906008-94-4

Other aromatic organo-sulfur compounds (excluding pesticides)

Formula: C₁₈H₁₄F₄N₂O₃S

Color and Shape: Solid

Molecular weight: 414.06613

Ref: 45-1A07540

Bicalutamide EP Impurity C (Deshydroxy Bicalutamide)

CAS: 906008-94-4

Formula: C₁₈H₁₄F₄N₂O₃S

Color and Shape: White To Off-White Solid

Molecular weight: 414.37

Ref: 4Z-B-0216

(2RS)-N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-methylpropanamide (Dehydroxybicalutamide)

CAS: 906008-94-4

Color and Shape: Neat

Ref: 86-MM0894.04

Bicalutamide EP Impurity C

CAS: 906008-94-4

Formula: C₁₈H₁₄F₄N₂O₃S

Molecular weight: 414.37

Ref: ST-EA-CP-B12003

Deshydroxy Bicalutamide

Controlled Product

CAS: 906008-94-4

Impurity Bicalutamide EP Impurity C
Applications Deshydroxy Bicalutamide (Bicalutamide EP Impurity C) is an impuirty of Bicalutamide. Bicalutamide intermediate.
References Lysiak, V., et al.: Bioorg. Med. Chem., 13, 671 (2005),

Formula: C₁₈H₁₄F₄N₂O₃S

Color and Shape: Off-White

Molecular weight: 414.37

Ref: TR-D289990

Deshydroxy bicalutamide

CAS: 906008-94-4

Deshydroxy bicalutamide is a ligand that has been synthesized to bind to the androgen receptor. It is an antagonist of the androgen receptor. Deshydroxy bicalutamide has been shown to inhibit cancer cell growth in prostate cancer cell lines, which is due to its ability to bind and block the ligand-binding domain of the androgen receptor. Molecular modelling has shown that deshydroxy bicalutamide binds in the hydroxyl group region of the binding site, which blocks it from binding with other ligands such as testosterone. This may lead to decreased levels of testosterone in males, leading to decreased levels of androgens in prostate cancer cells.

Formula: C₁₈H₁₄F₄N₂O₃S

Purity: Min. 95%

Molecular weight: 414.38 g/mol

Ref: 3D-FD21200