CAS 90632-33-0

Cyclophosphamide Impurity 8

Description:

Cyclophosphamide Impurity 8, with the CAS number 90632-33-0, is a chemical compound associated with the pharmaceutical agent cyclophosphamide, which is primarily used as a chemotherapy drug. This impurity is a byproduct that may arise during the synthesis or degradation of cyclophosphamide. While specific characteristics such as molecular weight, structure, and solubility may vary, impurities like this often exhibit similar chemical properties to their parent compounds. Cyclophosphamide itself is known for its alkylating properties, which interfere with DNA replication, making it effective against certain types of cancer. Impurities can impact the efficacy and safety profile of the drug, necessitating careful monitoring and characterization during pharmaceutical development. The presence of impurities can also influence the pharmacokinetics and pharmacodynamics of the drug, potentially leading to variations in therapeutic outcomes. Regulatory agencies typically require detailed analysis of such impurities to ensure drug quality and patient safety.

Formula: C₇H₁₇N₂O₄P

Synonyms:

• Ethanol, 2,2'-[(tetrahydro-2-oxido-2H-1,3,2-oxazaphosphorin-2-yl)imino]bis- (9CI)
• Cyclophosphamide Impurity 8
• Cyclophosphamide Impurity 15
• Didechlorodihydroxycyclophosphamide (Technical Grade)

Cyclophosphamide Impurity 15

CAS: 90632-33-0

Formula: C₇H₁₇N₂O₄P

Color and Shape: Off-White Semi-Solid

Molecular weight: 224.20

Ref: 4Z-C-10230

Didechlorodihydroxycyclophosphamide (Technical Grade)

Controlled Product

CAS: 90632-33-0

Applications Didechlorodihydroxycyclophosphamide is used in the preparation of cyclophosphamide metabolite in presence of cytochrome P 450 of liver microsomes. Cyclophosphamide is used in chemotherapy. It is a part of the standard treatment for patients with diffuse large-B-cell lymphoma.
References Clarke, Lynn, et al.: Cancer Res.,49,2344(1989); Bertrand, C., et al.: New Engl. J. Med., 346, 235 (2002)

Formula: C₇H₁₇N₂O₄P

Color and Shape: Neat

Molecular weight: 224.19

Ref: TR-D906320

Didechloro dihydroxy cyclophosphamide

CAS: 90632-33-0

Formula: C₇H₁₇N₂O₄P

Molecular weight: 224.2

Ref: ST-EA-CP-C37015