CymitQuimica logo

CAS 9068-38-6

:

RNA-dependent DNA polymerase

Description:
RNA-dependent DNA polymerase, also known as reverse transcriptase, is an enzyme that catalyzes the synthesis of DNA from an RNA template. This enzyme is crucial in the life cycle of retroviruses, allowing them to convert their RNA genome into DNA, which can then integrate into the host's genome. Characteristically, RNA-dependent DNA polymerase exhibits high fidelity in nucleotide incorporation, although it lacks proofreading ability, leading to a higher mutation rate compared to DNA polymerases. It typically operates in the presence of deoxynucleotide triphosphates (dNTPs) and requires a primer to initiate DNA synthesis. The enzyme is also notable for its role in molecular biology applications, such as the synthesis of complementary DNA (cDNA) from mRNA, which is essential for techniques like reverse transcription polymerase chain reaction (RT-PCR). Additionally, RNA-dependent DNA polymerase is a target for antiviral drugs, particularly in the treatment of HIV, as inhibiting its function can prevent viral replication. Its CAS number, 9068-38-6, identifies it in chemical databases, facilitating research and application in various scientific fields.
Formula:Unspecified
Synonyms:
  • AMV reverse transcriptase
  • Amv Rt
  • Cyscribe reverse transcriptase
  • Cyscript
  • DNA polymerase (reverse transcriptase)
  • DNA polymerase with intrinsic reverse transcriptase
  • DNA polymerase with reverse transcriptase
  • E.C. 2.7.7.49
  • Ec 2.7.7.49
  • Eiav Rt
  • See more synonyms
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 2 products.