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CAS 9073-60-3

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β-Lactamase

Description:
β-Lactamase is an enzyme that plays a crucial role in antibiotic resistance, particularly against β-lactam antibiotics such as penicillins and cephalosporins. It is produced by various bacteria, including both Gram-positive and Gram-negative species. The primary function of β-lactamase is to hydrolyze the β-lactam ring of these antibiotics, rendering them ineffective and allowing bacteria to survive in the presence of these drugs. The enzyme exhibits a range of characteristics, including its ability to vary in specificity and activity depending on the bacterial strain and the type of β-lactam antibiotic. β-Lactamases can be classified into different groups based on their molecular structure and mechanism of action, including serine β-lactamases and metallo-β-lactamases. The presence of β-lactamase genes in bacterial populations is a significant concern in clinical settings, as it contributes to the growing issue of antibiotic resistance, making infections harder to treat. Understanding the mechanisms and characteristics of β-lactamases is essential for developing new strategies to combat antibiotic-resistant infections.
Formula:Unspecified
Synonyms:
  • 3: PN: WO2019216248 SEQID: 10 claimed DNA
  • Carbapenamase
  • Carbapenem hydrolase
  • Carbapenem-hydrolyzing β-lactamase
  • Carbapenemase
  • Carbapenemase 1
  • Cefinase
  • Cefotaximase
  • Ceftazidimase
  • Ceftazimidase
  • See more synonyms
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products per page.Found 34 products.
  • LacBuster™-P bulk (β-lactamase)

    CAS:
    <p>Beta-lactamase enzyme targeting beta-lactam antibiotics</p>

    Ref: 3D-EBL040.5

    ne
    To inquire
  • LacBuster™ TSA broad range β-lactamase settle plates, 10 plates per pack, barcoded

    CAS:
    <p>A general purpose growth medium supplemented with LacBuster™ to effectively neutralize beta-lactam antibiotics. This product is suitable for the cultivation of a wide variety of microorganisms for environmental monitoring within the pharmaceutical industry and for high performance monitoring of your isolators and clean rooms during beta lactam manufacture</p>

    Ref: 3D-EBL065

    ne
    To inquire
  • LacBuster™ TSA broad range β-lactamase contact plates, 10 plates per pack, barcoded

    CAS:
    <p>A general purpose growth medium supplemented with LacBuster™ to effectively neutralize beta-lactam antibiotics. This product is suitable for the cultivation of a wide variety of microorganisms for environmental monitoring within the pharmaceutical industry and for high performance monitoring of your isolators and clean rooms during beta lactam manufacture</p>

    Ref: 3D-EBL066

    ne
    To inquire
  • LacBuster™ TSA broad range β-lactamase settle plates, 10 plates per pack, barcoded

    CAS:
    <p>A general purpose growth medium supplemented with LacBuster™ to effectively neutralize beta-lactam antibiotics. This product is suitable for the cultivation of a wide variety of microorganisms for environmental monitoring within the pharmaceutical industry and for high performance monitoring of your isolators and clean rooms during beta lactam manufacture</p>

    Ref: 3D-EBL063

    ne
    To inquire
  • LacBuster™ TSA broad range β-lactamase contact plates, 10 plates per pack, barcoded

    CAS:
    <p>A general purpose growth medium supplemented with LacBuster™ to effectively neutralize beta-lactam antibiotics. This product is suitable for the cultivation of a wide variety of microorganisms for environmental monitoring within the pharmaceutical industry and for high performance monitoring of your isolators and clean rooms during beta lactam manufacture</p>

    Ref: 3D-EBL064

    ne
    To inquire
  • LacBuster™-S 2000 (β-lactamase)

    CAS:
    <p>LacBuster™-S 2000 is an enzyme preparation, specifically a beta-lactamase, which is derived from bacterial sources known for their capacity to degrade beta-lactam antibiotics. Through hydrolytic cleavage of the beta-lactam ring, this enzyme neutralizes the efficacy of beta-lactam antibiotics, thereby rendering them inactive.</p>

    Ref: 3D-EBL023.2

    ne
    To inquire
  • LacBuster™-S 1000 (β-lactamase)

    CAS:
    <p>LacBuster™-S 1000 is an enzymatic product derived from microbial sources, specifically engineered for precision and efficiency. It is a beta-lactamase, which catalyzes the hydrolysis of the beta-lactam ring found in beta-lactam antibiotics such as penicillins and cephalosporins, rendering them inactive. The enzyme achieves this by breaking the amide bond within the beta-lactam ring, a critical structural component necessary for antibiotic activity.</p>

    Ref: 3D-EBL022.2

    ne
    To inquire
  • LacBuster™-S 5000 (β-lactamase)

    CAS:
    <p>LacBuster™-S 5000 is an enzymatic product, specifically a beta-lactamase, which originates from microbial sources known for their ability to produce enzymes that break down antibiotics. This product functions by hydrolyzing the beta-lactam ring of relevant antibiotics, thereby neutralizing their antibacterial activity.</p>

    Ref: 3D-EBL025.2

    ne
    To inquire
  • LacBuster™-S 50 (β-lactamase)

    CAS:
    <p>LacBuster™-S 50 is a beta-lactamase formulation, which is an enzyme of microbial origin with the ability to hydrolyze beta-lactam antibiotics. This enzymatic product is derived from specific bacterial species known for their resistance mechanisms, providing a robust capability to deactivate compounds such as penicillins and cephalosporins. Its mode of action involves the cleavage of the beta-lactam ring, a crucial structural component of these antibiotics, effectively neutralizing their antibacterial properties.</p>

    Ref: 3D-EBL021.2

    ne
    To inquire
  • LacBuster™-L concentrate

    CAS:
    <p>Beta-lactamase solution targeting beta-lactam antibiotics such as penicillins, carbapenems and cephalosporins. According to US Pharmacopeia (USP &lt;71&gt;) and EP, LacBusterTM-L is suitable for sterility testing methods such as membrane filtration and direct inoculation.</p>

    Ref: 3D-EBL019.7

    ne
    To inquire
  • LacBuster™-L 100 (beta-lactamase)

    CAS:
    <p>Ready to use beta-lactamase solution targeting beta-lactam antibiotics such as penicillins, carbapenems and cephalosporins. According to US Pharmacopeia (USP &lt;71&gt;) and EP, LacBusterTM-L is suitable for sterility testing methods such as membrane filtration and direct inoculation.beta lactamase I activity - min. 25.0 IU/mLbeta lactamase II activity - min. 10.0 IU/mL</p>

    Ref: 3D-EBL014.3

    1piece
    191.00€
  • LacBuster™ (b-lactamase) settle plates

    CAS:
    A general purpose growth medium supplemented with LacBuster™ to effectively neutralize beta-lactam antibiotics. This product is suitable for the cultivation of a wide variety of microorganisms for environmental monitoring within the pharmaceutical industry and for high performance monitoring of your isolators and clean rooms during beta lactam manufacture

    Ref: 3D-EBL061

    ne
    To inquire
  • CENTA(TM) β-LACTAMASE SUBSTRATE

    CAS:
    Formula:C21H17N3O8S3
    Color and Shape:Solid
    Molecular weight:535.5700

    Ref: IN-DA00GRR6

    ne
    Discontinued
    25mg
    Discontinued
    Discontinued product
  • LacBuster™ (b-lactamase) contact plates

    CAS:
    <p>A general purpose growth medium supplemented with LacBuster™ to effectively neutralize beta-lactam antibiotics. This product is suitable for the cultivation of a wide variety of microorganisms for environmental monitoring within the pharmaceutical industry and for high performance monitoring of your isolators and clean rooms during beta lactam manufacture</p>

    Ref: 3D-EBL062

    ne
    Discontinued
    Discontinued product