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CAS 9075-65-4

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Glycerol phosphate dehydrogenase

Description:
Glycerol phosphate dehydrogenase (GPDH) is an enzyme that plays a crucial role in the metabolism of glycerol and the regulation of energy production in cells. It catalyzes the reversible conversion of glycerol-3-phosphate to dihydroxyacetone phosphate, linking carbohydrate and lipid metabolism. This enzyme is found in various organisms, including bacteria, plants, and animals, and is particularly important in tissues such as the liver and muscle. GPDH is involved in the glycerol phosphate shuttle, which facilitates the transfer of reducing equivalents across mitochondrial membranes, thus contributing to ATP production. The enzyme's activity can be influenced by factors such as pH, temperature, and the presence of cofactors like NAD+ or NADH. Glycerol phosphate dehydrogenase is also of interest in clinical research, as alterations in its activity may be associated with metabolic disorders and conditions such as diabetes. Its CAS number, 9075-65-4, identifies it in chemical databases, aiding in the study and application of this enzyme in biochemistry and biotechnology.
Formula:NULL
Synonyms:
  • <span class="text-smallcaps">L</span>-Glycerol phosphate dehydrogenase
  • <span class="text-smallcaps">L</span>-Glycerophosphate dehydrogenase
  • <span class="text-smallcaps">L</span>-α-Glycerol phosphate dehydrogenase
  • <span class="text-smallcaps">L</span>-α-Glycerophosphate dehydrogenase
  • A-glycerophosphate dehydrogenase type I from rabb
  • Dehydrogenase, Glycerinphosphat
  • Dehydrogenase, glycerol phosphate
  • Deshidrogenasa, Glicerol Fosfato
  • Deshydrogenase, Glycerol Phosphate
  • E.C. 1.1.1.8
  • See more synonyms
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