CAS 90779-69-4

Atosiban

Description:

Atosiban is a synthetic peptide that functions as an oxytocin receptor antagonist, primarily used in obstetrics to inhibit premature labor. Its chemical structure is characterized by a sequence of amino acids that mimic the natural hormone oxytocin, allowing it to bind to the same receptors but block their activation. This action helps to relax uterine contractions, making it a valuable therapeutic agent in managing preterm labor. Atosiban is typically administered intravenously and has a relatively short half-life, necessitating careful monitoring during treatment. The substance is known for its specificity to the oxytocin receptor, which minimizes side effects compared to other tocolytic agents. In terms of solubility, atosiban is generally soluble in water, which facilitates its intravenous administration. Its pharmacokinetics and pharmacodynamics are well-studied, contributing to its clinical use in obstetric care. Overall, atosiban represents a targeted approach to managing preterm labor, with a focus on receptor-specific action to minimize adverse effects.

Formula: C₄₃H₆₇N₁₁O₁₂S₂

InChI: InChI=1/C43H67N11O12S2/c1-5-23(3)35-41(63)53-36(24(4)55)42(64)50-29(20-32(45)56)38(60)51-30(43(65)54-17-8-10-31(54)40(62)49-27(9-7-16-44)37(59)47-21-33(46)57)22-68-67-18-15-34(58)48-28(39(61)52-35)19-25-11-13-26(14-12-25)66-6-2/h11-14,23-24,27-31,35-36,55H,5-10,15-22,44H2,1-4H3,(H2,45,56)(H2,46,57)(H,47,59)(H,48,58)(H,49,62)(H,50,64)(H,51,60)(H,52,61)(H,53,63)/t23-,24+,27-,28+,29-,30-,31-,35-,36?/m0/s1

Synonyms:

• Atosiban [USAN:INN]
• Rwj 22164
• 1-(3-Mercaptopropionic acid)-2-(3-(p-ethoxyphenyl)-D-alanine)-4-L-threonine-8-L-ornithineoxytocin
• 1-Deamino-2D-tyr-(OEt)-4-thr-8-orn-oxytocin
• Atosibanum
• Atosibanum [INN-Latin]
• Orf 22164
• Tractocile
• Unii-081D12Si0Z
• Oxytocin, 1-(3-mercaptopropanoic acid)-2-(O-ethyl-D-tyrosine)-4-L-threonine-8-L-ornithine-
• 1-({(4R,7S,13S,16R)-7-(2-amino-2-oxoethyl)-13-[(2S)-butan-2-yl]-16-(4-ethoxybenzyl)-10-[(1R)-1-hydroxyethyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl}carbonyl)-L-prolyl-L-ornithylglycinamide

Atosiban

CAS: 90779-69-4

Oxytocin/vasopressin receptor antagonist.

Formula: C₄₃H₆₇N₁₁O₁₂S₂

Purity: 99.4%

Color and Shape: White

Molecular weight: 994.2

Ref: 01-4065438

Atosiban

CAS: 90779-69-4

Atosiban

Purity: 99.2% by hplc (Typical Value in Batch COA)

Color and Shape: sterile filtered white lyophilized (freeze-dried) powder.

Molecular weight: 994.19g/mol

Ref: 54-BITH3004

Atosiban

CAS: 90779-69-4

Formula: C₄₃H₆₇N₁₁O₁₂S₂

Purity: ≥ 98%

Color and Shape: White to off-white powder

Molecular weight: 994.19

Ref: 7W-GL1053

Atosiban

CAS: 90779-69-4

Atosiban (RW22164), an oxytocin/vasopressin inhibitor, halts premature labor as an intravenous tocolytic, reducing uterine contractions rapidly.

Formula: C₄₃H₆₇N₁₁O₁₂S₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 994.19

Ref: TM-T4996

Atosiban Acetate

CAS: 90779-69-4

Formula: C₄₃H₆₇N₁₁O₁₂S₂

Purity: 95%~99%

Color and Shape: White to Off-white Powder

Molecular weight: 994.189

Ref: BP-BPPG008