CAS 90808-12-1

Divaplon

Description:

Divaplon, with the CAS number 90808-12-1, is a chemical compound that belongs to the class of non-benzodiazepine anxiolytics. It is primarily characterized by its role as a selective modulator of the GABA-A receptor, which is crucial for its anxiolytic effects. Divaplon exhibits a unique pharmacological profile, providing anxiolytic properties without the sedative effects commonly associated with traditional benzodiazepines. This makes it an interesting candidate for the treatment of anxiety disorders. The compound is typically administered orally and has been studied for its potential to improve anxiety symptoms while minimizing the risk of dependence and withdrawal associated with other anxiolytics. Additionally, Divaplon has been evaluated for its safety and efficacy in clinical trials, although its development has faced challenges. Overall, its distinct mechanism of action and therapeutic potential highlight its significance in the field of psychopharmacology.

Formula: C₁₇H₁₇N₃O₂

InChI: InChI=1S/C17H17N3O2/c1-4-13-11(2)20-10-14(18-17(20)19-16(13)22-3)15(21)12-8-6-5-7-9-12/h5-10H,4H2,1-3H3

InChI key: InChIKey=NRJVHCSYLGLURI-UHFFFAOYSA-N

SMILES: CC=1N2C(=NC(C(=O)C3=CC=CC=C3)=C2)N=C(OC)C1CC

Synonyms:

• Divaplone [INN-French]
• Methanone, (6-ethyl-7-methoxy-5-methylimidazo(1,2-a)pyrimidin-2-yl)phenyl-
• (6-ethyl-7-methoxy-5-methylimidazo[1,2-a]pyrimidin-2-yl)(phenyl)methanone
• 6-Ethyl-7-methoxy-5-methylimidazo(1,2-a)pyrimidin-2-yl phenyl ketone
• Divaplon
• RU 32698
• Methanone, (6-ethyl-7-methoxy-5-methylimidazo[1,2-a]pyrimidin-2-yl)phenyl-
• Divaplon [INN]
• RU 32698
• UNII-4AOV43246G
• Imidazo[1,2-a]pyrimidine, methanone deriv.
• Divaplonum [INN-Latin]
• (6-Ethyl-7-methoxy-5-methylimidazo[1,2-a]pyrimidin-2-yl)phenylmethanone
• Divaplone

Divaplon

CAS: 90808-12-1

Divaplon

Purity: ≥95%

Molecular weight: 295.34g/mol

Ref: 54-BUP03522

Divaplon

CAS: 90808-12-1

Divaplon is a GABA receptor agonist (IC50: 0.056 µM) that displays non-sedating anxiolytic behavioral characteristics in a rat model of anxiety.

Formula: C₁₇H₁₇N₃O₂

Purity: 97.44% - 98.25%

Color and Shape: Solid

Molecular weight: 295.34

Ref: TM-T27186