CAS 90866-33-4

(R)-(+)-ethyl-4-chloro-3-hydroxybutanoate

Description:

(R)-(+)-ethyl-4-chloro-3-hydroxybutanoate is an organic compound characterized by its chiral nature, which is indicated by the (R)- configuration. This compound features a chloro substituent at the fourth carbon and a hydroxy group at the third carbon of a butanoate chain, contributing to its reactivity and potential applications in synthesis. It is an ester, derived from the reaction of a carboxylic acid and an alcohol, specifically ethyl alcohol in this case. The presence of the hydroxy group suggests it may participate in hydrogen bonding, influencing its solubility and boiling point. The chloro group can also serve as a site for nucleophilic substitution reactions, making it a valuable intermediate in organic synthesis. This compound is typically used in pharmaceutical research and development, particularly in the synthesis of biologically active molecules. Its specific stereochemistry can affect the biological activity and interaction with other molecules, making it important in chiral synthesis and drug design.

Formula: C₆H₁₁ClO₃

InChI: InChI=1/C6H11ClO3/c1-2-10-6(9)3-5(8)4-7/h5,8H,2-4H2,1H3

SMILES: CCOC(=O)CC(CCl)O

Synonyms:

• Ethyl (R)-(+)-4-chloro-3-hydroxybutyrate
• (R)-(+)-4-Chloro-
• 3-hydroxybutyric acid ethyl ester
• (R)-4-chloro-3-hydroxybutyric acid ethyl ester
• (R)-4-Chloro-3-hydroxybutanoic acid ethyl ester
• Ethyl (R)-4-chloro-3-Hydroxybutanoate
• butanoic acid, 4-chloro-3-hydroxy-, Ethyl ESTER,(R)
• 4-Chloro-3-hydroxybutyric acid ethyl ester
• (R)-(+)-Ethyl-4-chloro-3-hydroxybutyrate
• Ethyl(R)-(+)-4-chloro-3-hydroxy butyrate
• R(+)-Ethyl-4-Chloro-3-Hydroxybutanoate

Ethyl (R)-(+)-4-chloro-3-hydroxybutyrate, 97%, ee 96%

CAS: 90866-33-4

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₆H₁₁ClO₃

Purity: 96%

Color and Shape: Clear colorless, Liquid

Molecular weight: 166.60

Ref: 02-L18553

Ethyl (R)-(+)-4-Chloro-3-Hydroxybutyrate

CAS: 90866-33-4

Formula: C₆H₁₁ClO₃

Purity: 97%

Color and Shape: Liquid

Molecular weight: 166.6027

Ref: IN-DA0034TR

Ethyl (R)-(+)-4-chloro-3-hydroxybutyrate

CAS: 90866-33-4

Ethyl (R)-(+)-4-chloro-3-hydroxybutyrate

Purity: 98%

Molecular weight: 166.60g/mol

Ref: 54-OR912444

Ethyl (R)-(+)-4-chloro-3-hydroxybutyrate

CAS: 90866-33-4

Formula: C₆H₁₁ClO₃

Molecular weight: 166.61

Ref: 7W-GK7449

Ethyl (R)-4-Chloro-3-hydroxybutanoate

CAS: 90866-33-4

Formula: C₆H₁₁ClO₃

Purity: >97.0%(GC)

Color and Shape: Colorless to Light yellow clear liquid

Molecular weight: 166.60

Ref: 3B-E1527

Empagliflozin Impurity 129

CAS: 90866-33-4

Formula: C₆H₁₁ClO₃

Molecular weight: 166.60

Ref: 4Z-E-63149

(R)-Ethyl 4-chloro-3-hydroxybutanoate

CAS: 90866-33-4

Formula: C₆H₁₁ClO₃

Purity: 95%

Color and Shape: Liquid

Molecular weight: 166.6

Ref: 10-F079716

(R)-Ethyl 4-Chloro-3-hydroxybutanoate (~90%)

Controlled Product

CAS: 90866-33-4

Applications (R)-Ethyl 4-chloro-3-hydroxybutanoate is used in biological studies for asymmetric reduction of ethyl 4-chloro-3-oxobutanoate to ethyl (R)-4-chloro-3-hydroxybutanoate with two co-existing, recombinant Escherichia coli strains.
References Liu, Y., et al.: Biotech. Lett., 27, 119 (2005);

Formula: C₆H₁₁ClO₃

Purity: ~90%

Color and Shape: Neat

Molecular weight: 166.6

Ref: TR-E901985

Ethyl (R)-(+)-4-chloro-3-hydroxybutyrate

CAS: 90866-33-4

Ethyl (R)-(+)-4-chloro-3-hydroxybutyrate is a chiral compound with two stereoisomers, one of which is the natural form. It can be synthesized by asymmetric synthesis from ethylene diamine and acetaldehyde. This reaction is catalysed by enzymes such as dehydrogenase, which are used in the biosynthesis of other compounds. The enzyme catalysis results in a high activation energy. Ethyl (R)-(+)-4-chloro-3-hydroxybutyrate also has an organic solvent that is required for its synthesis, d-xylose. The enzyme expression plasmid that is used to express this compound requires recombinant cells.

Formula: C₆H₁₁ClO₃

Purity: Min. 95%

Color and Shape: Clear Liquid

Molecular weight: 166.6 g/mol

Ref: 3D-FE33805