CAS 908847-01-8

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-6-fluoro-L-tryptophan

Description:

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-6-fluoro-L-tryptophan, commonly referred to as Fmoc-6-fluoro-L-tryptophan, is a derivative of the amino acid tryptophan, modified to include a fluorenylmethoxycarbonyl (Fmoc) protecting group and a fluorine atom at the 6-position of the indole ring. This compound is characterized by its role in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS), where the Fmoc group serves as a protective group for the amino functionality, allowing for selective deprotection and coupling reactions. The presence of the fluorine atom can enhance the compound's biochemical properties, potentially influencing its interactions in biological systems. Fmoc-6-fluoro-L-tryptophan is typically a white to off-white solid, and its solubility is generally in organic solvents, making it suitable for various synthetic applications. Its unique structure and properties make it valuable in the development of peptide-based therapeutics and research in medicinal chemistry.

Formula: C₂₆H₂₁FN₂O₄

InChI: InChI=1S/C26H21FN2O4/c27-16-9-10-17-15(13-28-23(17)12-16)11-24(25(30)31)29-26(32)33-14-22-20-7-3-1-5-18(20)19-6-2-4-8-21(19)22/h1-10,12-13,22,24,28H,11,14H2,(H,29,32)(H,30,31)/t24-/m0/s1

InChI key: InChIKey=ZNQAUDMHOJUTJL-DEOSSOPVSA-N

SMILES: C(OC(N[C@@H](CC=1C=2C(NC1)=CC(F)=CC2)C(O)=O)=O)C3C=4C(C=5C3=CC=CC5)=CC=CC4

Synonyms:

• N-Fmoc-6-fluoro-L-tryptophan
• N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-6-fluoro-L-tryptophan
• L-Tryptophan, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-6-fluoro-
• (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(6-fluoro-1H-indol-3-yl)propanoic acid
• (9H-Fluoren-9-yl)MethOxy]Carbonyl L-Trp(6-F)-OH
• (2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-(6-fluoro-1H-indol-3-yl)propanoic acid
• Fmoc-L-Trp(6-F)-OH
• N-α-(9-Fluorenylmethoxycarbonyl)-6-fluoro-L-tryptophan

N-Fmoc-6-fluoro-L-tryptophan

CAS: 908847-01-8

Formula: C₂₆H₂₁FN₂O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 444.4543

Ref: IN-DA00GXJI

N-Fmoc-6-Fluoro-L-tryptophan

CAS: 908847-01-8

N-Fmoc-6-Fluoro-L-tryptophan

Purity: 95%

Molecular weight: 444.45g/mol

Ref: 54-PC27891

N-Fmoc-6-fluoro-L-tryptophan

CAS: 908847-01-8

N-Fmoc-6-fluoro-L-tryptophan is a useful scaffold that can be used as a building block for the synthesis of complex compounds. It is an intermediate in the synthesis of several pharmaceuticals and speciality chemicals. N-Fmoc-6-fluoro-L-tryptophan is a versatile building block that can be used to make fine chemicals such as drugs, pesticides, dyes, and perfumes.

Formula: C₂₆H₂₁FN₂O₄

Purity: Min. 98 Area-%

Color and Shape: White Powder

Molecular weight: 444.45 g/mol

Ref: 3D-FF79053

(S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(6-fluoro-1H-indol-3-yl)propanoic acid

CAS: 908847-01-8

Purity: 98%

Color and Shape: Solid

Molecular weight: 444.4620056

Ref: 10-F779330

N-Fmoc-6-fluoro-L-tryptophan

Controlled Product

CAS: 908847-01-8

Formula: C₂₆H₂₁FN₂O₄

Color and Shape: Neat

Molecular weight: 444.454

Ref: TR-F622900