CAS 908847-42-7

(2S)-3-(6-chloro-1H-indol-3-yl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid

Description:

The chemical substance known as (2S)-3-(6-chloro-1H-indol-3-yl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid, with the CAS number 908847-42-7, is a synthetic compound that features a complex structure incorporating an indole moiety and a fluorenylmethoxycarbonyl (Fmoc) group. This compound is characterized by its chiral center at the second carbon of the propanoic acid backbone, which contributes to its stereochemical properties. The presence of the 6-chloro substituent on the indole ring enhances its potential biological activity, possibly influencing interactions with biological targets. The Fmoc group is commonly used in peptide synthesis as a protective group for amino acids, indicating that this compound may play a role in the development of peptide-based therapeutics or research applications. Its solubility, stability, and reactivity would depend on the specific conditions, such as pH and solvent, making it suitable for various chemical and biological studies. Overall, this compound exemplifies the intricate design often found in pharmaceutical chemistry.

Formula: C₂₆H₂₁ClN₂O₄

InChI: InChI=1/C26H21ClN2O4/c27-16-9-10-17-15(13-28-23(17)12-16)11-24(25(30)31)29-26(32)33-14-22-20-7-3-1-5-18(20)19-6-2-4-8-21(19)22/h1-10,12-13,22,24,28H,11,14H2,(H,29,32)(H,30,31)/t24-/m0/s1

SMILES: c1ccc2c(c1)c1ccccc1C2COC(=N[C@@H](Cc1c[nH]c2cc(ccc12)Cl)C(=O)O)O

Synonyms:

• 6-Chloro-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-tryptophan
• L-Tryptophan, 6-chloro-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
• Fmoc-Trp(6-Cl)-OH
• Fmoc-6-chloro L-Tryptophan USP/EP/BP
• Fmoc-6-chloro-L-tryptophane
• Fmoc-L-(Chloro)-Trp-OH
• FMoc-6-chloro (S)-Tryptophan
• Fmoc-6-chloro L-Tryptophan
• (S)-2-((((9H-Fluoren-9-yl)Methoxy)carbonyl)aMino)-3-(6-chloro-1H-indol-3-yl)propanoic acid
• (2S)-3-(6-chloro-1H-indol-3-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid
• N-α-(9-Fluorenylmethoxycarbonyl)-6-chloro-L-tryptophan
• 6-Chloro-N-Fmoc-L-tryptophan
• Fmoc-L-6-Chlorotryptophan

Fmoc-6-chloro L-tryptophan

CAS: 908847-42-7

Formula: C₂₆H₂₁ClN₂O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 460.9089

Ref: IN-DA003QMQ

Fmoc-6-chloro L-tryptophan

CAS: 908847-42-7

Formula: C₂₆H₂₁ClN₂O₄

Purity: ≥ 99.0%

Color and Shape: White powder

Molecular weight: 460.91

Ref: 7W-GM8874

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(6-chloro-1H-indol-3-yl)propanoic acid

CAS: 908847-42-7

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(6-chloro-1H-indol-3-yl)propanoic acid

Purity: 97%

Molecular weight: 460.91g/mol

Ref: 54-OR76144

Fmoc-6-chloro L-tryptophan

CAS: 908847-42-7

Fmoc-6-chloro L-tryptophan is a heterocycle with methylene and active methylene groups that can be used as a building block for 1,3-dipolar cycloadditions. It has been shown to react with perchlorates in the presence of catalysts such as dibromodifluoromethane (DBDM) and perchloric acid to form an exocyclic azomethine imine. This reaction generates a proton, which shifts the equilibrium to the right, forming more product. The optimal conditions for this reaction are pH 8, 50% DBDM, and 10% HClO4.

Formula: C₂₆H₂₁ClN₂O₄

Purity: Min. 97 Area-%

Color and Shape: White Powder

Molecular weight: 460.91 g/mol

Ref: 3D-FF23534

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(6-chloro-1H-indol-3-yl)propanoic acid

CAS: 908847-42-7

Purity: 98%

Molecular weight: 460.9100037

Ref: 10-F791595

Fmoc-6-chloro L-Tryptophan

Controlled Product

CAS: 908847-42-7

Applications Used for preparation of acyltryptophanols as FSH antagonists.

Formula: C₂₆H₂₁ClN₂O₄

Color and Shape: Neat

Molecular weight: 460.91

Ref: TR-F628005