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CAS 909-39-7

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Opipramol hydrochloride

Description:
Opipramol hydrochloride is a pharmaceutical compound primarily used as an anxiolytic and antidepressant. It belongs to the class of dibenzodiazepines and exhibits a unique mechanism of action, which includes serotonin and norepinephrine reuptake inhibition, as well as modulation of the sigma receptors. This dual action contributes to its efficacy in treating anxiety disorders and depressive symptoms. The substance is typically administered in its hydrochloride salt form, enhancing its solubility and bioavailability. Opipramol is characterized by its relatively low toxicity profile, but it can cause side effects such as sedation, dizziness, and gastrointestinal disturbances. Its pharmacokinetics involve oral administration, with a moderate half-life, allowing for once or twice daily dosing. The compound is not classified as a controlled substance in many regions, making it more accessible for therapeutic use. Overall, Opipramol hydrochloride is recognized for its therapeutic benefits in managing anxiety and depressive disorders, although careful monitoring is advised due to potential side effects and interactions with other medications.
Formula:C23H29N3O·2ClH
InChI:InChI=1S/C23H29N3O.2ClH/c27-19-18-25-16-14-24(15-17-25)12-5-13-26-22-8-3-1-6-20(22)10-11-21-7-2-4-9-23(21)26;;/h1-4,6-11,27H,5,12-19H2;2*1H
InChI key:InChIKey=DLTOEESOSYKJBK-UHFFFAOYSA-N
SMILES:C(CCN1CCN(CCO)CC1)N2C=3C(C=CC=4C2=CC=CC4)=CC=CC3.Cl
Synonyms:
  • 1-Piperazineethanol, 4-[3-(5H-dibenz[b,f]azepin-5-yl)propyl]-, dihydrochloride
  • 1-Piperazineethanol, 4-[3-(5H-dibenz[b,f]azepin-5-yl)propyl]-, hydrochloride (1:2)
  • 2-{4-[3-(5H-dibenzo[b,f]azepin-5-yl)propyl]piperazin-1-yl}ethanol
  • 2-{4-[3-(5H-dibenzo[b,f]azepin-5-yl)propyl]piperazin-1-yl}ethanol dihydrochloride
  • 4-[3-(5H-Dibenz[b,f]azepin-5-yl)propyl]-1-piperazineethanol dihydrochloride
  • 5-[γ-(β-Hydroxyethylpiperazino)propyl]-5H-dibenzo[b,f]azepine dihydrochloride
  • 5H-Dibenz[b,f]azepine, 1-piperazineethanol deriv.
  • Dinsidon
  • G 33040
  • Insidon
  • See more synonyms
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