CAS 909-39-7

Opipramol hydrochloride

Description:

Opipramol hydrochloride is a pharmaceutical compound primarily used as an anxiolytic and antidepressant. It belongs to the class of dibenzodiazepines and exhibits a unique mechanism of action, which includes serotonin and norepinephrine reuptake inhibition, as well as modulation of the sigma receptors. This dual action contributes to its efficacy in treating anxiety disorders and depressive symptoms. The substance is typically administered in its hydrochloride salt form, enhancing its solubility and bioavailability. Opipramol is characterized by its relatively low toxicity profile, but it can cause side effects such as sedation, dizziness, and gastrointestinal disturbances. Its pharmacokinetics involve oral administration, with a moderate half-life, allowing for once or twice daily dosing. The compound is not classified as a controlled substance in many regions, making it more accessible for therapeutic use. Overall, Opipramol hydrochloride is recognized for its therapeutic benefits in managing anxiety and depressive disorders, although careful monitoring is advised due to potential side effects and interactions with other medications.

Formula: C₂₃H₂₉N₃O·2ClH

InChI: InChI=1S/C23H29N3O.2ClH/c27-19-18-25-16-14-24(15-17-25)12-5-13-26-22-8-3-1-6-20(22)10-11-21-7-2-4-9-23(21)26;;/h1-4,6-11,27H,5,12-19H2;2*1H

InChI key: InChIKey=DLTOEESOSYKJBK-UHFFFAOYSA-N

SMILES: C(CCN1CCN(CCO)CC1)N2C=3C(C=CC=4C2=CC=CC4)=CC=CC3.Cl

Synonyms:

• 1-Piperazineethanol, 4-[3-(5H-dibenz[b,f]azepin-5-yl)propyl]-, dihydrochloride
• 1-Piperazineethanol, 4-[3-(5H-dibenz[b,f]azepin-5-yl)propyl]-, hydrochloride (1:2)
• 2-{4-[3-(5H-dibenzo[b,f]azepin-5-yl)propyl]piperazin-1-yl}ethanol
• 2-{4-[3-(5H-dibenzo[b,f]azepin-5-yl)propyl]piperazin-1-yl}ethanol dihydrochloride
• 4-[3-(5H-Dibenz[b,f]azepin-5-yl)propyl]-1-piperazineethanol dihydrochloride
• 5-[γ-(β-Hydroxyethylpiperazino)propyl]-5H-dibenzo[b,f]azepine dihydrochloride
• 5H-Dibenz[b,f]azepine, 1-piperazineethanol deriv.
• Dinsidon
• G 33040
• Insidon
• Insidone
• Nisidana
• Opipramol HCL
• Opipramol hydrochloride

Opipramol Dihydrochloride

CAS: 909-39-7

Color and Shape: Neat

Ref: 61-FOR0422.00

Opipramol dihydrochloride

CAS: 909-39-7

Formula: C₂₃H₂₉N₃O·2HCl

Purity: 98.0 - 101.0 % (dried basis)

Color and Shape: Yellow to green-yellow powder

Molecular weight: 436.42

Ref: 7W-GL4485

Opipramol Dihydrochloride

CAS: 909-39-7

Formula: C₂₃H₂₉N₃OClH

Color and Shape: White

Molecular weight: 436.42

Ref: 86-MM0422.00

Opipramol dihydrochloride

Controlled Product

CAS: 909-39-7

Formula: C₂₃H₂₉N₃OClH

Color and Shape: Neat

Molecular weight: 436.42

Ref: 04-C15732000

Opipramol dihydrochloride

CAS: 909-39-7

Opipramol (Ensidon) is an atypical tricyclic antidepressant (TCA) primarily functioning as a sigma (σ) receptor agonist. It interacts effectively with sigma recognition sites, having a Ki value of 50 nM. Opipramol is applicable in the study of generalized anxiety disorder (GAD).

Formula: C₂₃H₃₁Cl₂N₃O

Color and Shape: Solid

Molecular weight: 436.418

Ref: TM-T204660