CAS 90965-06-3

(1Z)-1-diazonio-1-(dimethoxyphosphoryl)prop-1-en-2-olate

Description:

(1Z)-1-diazonio-1-(dimethoxyphosphoryl)prop-1-en-2-olate, with CAS number 90965-06-3, is a chemical compound characterized by its diazonium functionality, which typically imparts unique reactivity, particularly in electrophilic aromatic substitution reactions. The presence of the dimethoxyphosphoryl group suggests that it may exhibit properties associated with phosphonate esters, including potential applications in organic synthesis and as intermediates in the preparation of various phosphorus-containing compounds. The prop-1-en-2-olate structure indicates that it possesses an enolate form, which can participate in nucleophilic reactions, making it a versatile building block in synthetic chemistry. Additionally, the compound's stability and reactivity can be influenced by the presence of the diazonium group, which can be sensitive to heat and light. Overall, this compound may be of interest in fields such as medicinal chemistry, agrochemicals, and materials science due to its unique structural features and potential reactivity.

Formula: C₅H₉N₂O₄P

InChI: InChI=1/C5H9N2O4P/c1-4(8)5(7-6)12(9,10-2)11-3/h1-3H3

SMILES: CC(=O)C(=P([O-])(OC)OC)[N+]#N

Synonyms:

• (1-Diazo-2-oxopropyl)phosphonic acid dimethyl ester
• Dimethyl (1-Diazo-2-oxopropyl)phosphonate
• Nnyv1&Po&O1&O1
• Phosphonic acid, P-(1-diazo-2-oxopropyl)-, dimethyl ester

Dimethyl (1-Diazo-2-oxopropyl)phosphonate (10% in Acetonitrile)

CAS: 90965-06-3

Formula: C₅H₉N₂O₄P

Color and Shape: Light yellow to Yellow to Orange clear liquid

Molecular weight: 192.11

Ref: 3B-D5048

Dimethyl (1-Diazo-2-oxopropyl)phosphonate

CAS: 90965-06-3

Formula: C₅H₉N₂O₄P

Purity: >97.0%(HPLC)

Color and Shape: Light yellow to Brown clear liquid

Molecular weight: 192.11

Ref: 3B-D3546

Dimethyl (1-diazo-2-oxopropyl)phosphonate

CAS: 90965-06-3

Formula: C₅H₉N₂O₄P

Purity: 95%

Color and Shape: Liquid

Molecular weight: 192.1097

Ref: IN-DA003660

Dimethyl (1-diazo-2-oxo-prop-1-yl)phosphonate

CAS: 90965-06-3

Dimethyl (1-diazo-2-oxo-prop-1-yl)phosphonate

Formula: C₅H₉N₂O₄P

Purity: 95%

Color and Shape: clear. dark yellow liquid

Molecular weight: 192.10972g/mol

Ref: 54-OR313045

Dimethyl (1-diazo-2-oxo-propyl)phosphonate

CAS: 90965-06-3

Formula: C₅H₉N₂O₄P

Purity: 95.0%

Color and Shape: Liquid, Clear

Molecular weight: 192.111

Ref: 10-F049853

Ohira-Bestmann Reagent Solution

CAS: 90965-06-3

Ref: 7W-GW2761

Ohira-Bestmann Reagent

CAS: 90965-06-3

Ref: 7W-GW0498

Dimethyl (1-Diazo-2-oxopropyl)phosphonate

Controlled Product

CAS: 90965-06-3

Applications Dimethyl (1-Diazo-2-oxopropyl)phosphonate is a chemical reagent used in the synthesis of vacuolar type ATPase inhibitor Bafilomycin (B110000), which is used to counter age-related diseases. Also used in the synthesis of novel fluorinated derivatices of TSP 18 kDa ligand SSR18075 which are promising candidates for drug development or PET probes for in viv neuroinflammation imaging.
References Shibata, H. et al.: Chem. Asian J., 10, 915 (2015); Damont, A. et al.: Eur. j. Med. Chem., 101, 736 (2015);

Formula: C₅H₉N₂O₄P

Color and Shape: Neat

Molecular weight: 192.11

Ref: TR-D471815

1-Diazoacetonylphosphonic acid dimethyl ester

CAS: 90965-06-3

1-Diazoacetonylphosphonic acid dimethyl ester is an antimicrobial agent that has been shown to be active against Candida species and other fungi. The compound was synthesized using a modified Ugi four-component reaction, which enabled the preparation of a single asymmetric synthesis. This process also generated a new bioactive molecule, 1-aminoacetonylphosphonic acid, in high yield and with excellent enantioselectivity.

Formula: C₅H₉N₂O₄P

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 192.11 g/mol

Ref: 3D-FD33893