CAS 909725-61-7

P-[(3R)-3-Amino-4-[(3-hexylphenyl)amino]-4-oxobutyl]phosphonic acid

Description:

P-[(3R)-3-Amino-4-[(3-hexylphenyl)amino]-4-oxobutyl]phosphonic acid, with CAS number 909725-61-7, is a phosphonic acid derivative characterized by its complex structure that includes an amino group and a ketone functionality. This compound features a phosphonic acid moiety, which is known for its strong affinity for metal ions and potential applications in various fields, including agriculture and pharmaceuticals. The presence of the hexylphenyl group contributes to its hydrophobic characteristics, potentially influencing its solubility and interaction with biological membranes. The stereochemistry indicated by the (3R) configuration suggests specific spatial arrangements that may affect the compound's biological activity and reactivity. Overall, this substance may exhibit unique properties due to its combination of functional groups, making it a subject of interest for further research in medicinal chemistry and material science. Its synthesis and characterization would typically involve standard organic chemistry techniques, and its applications could range from drug development to agricultural formulations.

Formula: C₁₆H₂₇N₂O₄P

InChI: InChI=1S/C16H27N2O4P/c1-2-3-4-5-7-13-8-6-9-14(12-13)18-16(19)15(17)10-11-23(20,21)22/h6,8-9,12,15H,2-5,7,10-11,17H2,1H3,(H,18,19)(H2,20,21,22)/t15-/m1/s1

InChI key: InChIKey=FWJRVGZWNDOOFH-OAHLLOKOSA-N

SMILES: N(C([C@@H](CCP(=O)(O)O)N)=O)C1=CC(CCCCCC)=CC=C1

Synonyms:

• Phosphonic acid, P-[(3R)-3-amino-4-[(3-hexylphenyl)amino]-4-oxobutyl]-
• Phosphonic acid, [(3R)-3-amino-4-[(3-hexylphenyl)amino]-4-oxobutyl]-
• W 146
• P-[(3R)-3-Amino-4-[(3-hexylphenyl)amino]-4-oxobutyl]phosphonic acid
• ML 056

[(3R)-3-aMino-4-[(3-hexylphenyl)aMino]-4-oxobutyl]-phosphonic acid

CAS: 909725-61-7

Formula: C₁₆H₂₇N₂O₄P

Purity: 98%

Color and Shape: Solid

Molecular weight: 342.3703

Ref: IN-DA006SHS

W146

CAS: 909725-61-7

W146

Purity: ≥98%

Molecular weight: 342.37g/mol

Ref: 54-BUP04513

W146

CAS: 909725-61-7

W146 is a small molecule inhibitor of matrix metalloproteinase-9 (MMP-9) that has been shown to be neuroprotective in an animal model of cerebral ischemia. It attenuated neuronal death and reduced the expression of pro-inflammatory cytokines and chemokines after transient focal cerebral ischemia. W146 binds to the active site of MMP-9, preventing it from cleaving a critical protein substrate, which prevents the activation of downstream signaling pathways. This drug also inhibits transcriptional activity and polymerase chain reaction (PCR). W146 has been shown to have anti-inflammatory properties in granulosa cells by inhibiting the production of cytokines and chemokines, such as IL-1β, IL-6, IL-8, TNFα, and MCP-1.

Formula: C₁₆H₂₇N₂O₄P

Purity: Min. 95%

Molecular weight: 342.37 g/mol

Ref: 3D-JLB72561

W146

CAS: 909725-61-7

W146 is an S1PR1 antagonist that induces a significant but transient decrease in blood lymphocytes in mice.

Formula: C₁₆H₂₇N₂O₄P

Purity: 99.37%

Color and Shape: Solid

Molecular weight: 342.37

Ref: TM-T13327