CAS 90986-52-0

Janthitrem F

Description:

Janthitrem F, with the CAS number 90986-52-0, is a chemical compound that belongs to the class of alkaloids, specifically a type of indole alkaloid. It is primarily known for its occurrence in certain fungal species, particularly those within the genus Penicillium. Janthitrem F exhibits notable biological activity, including potential neurotoxic effects, which has garnered interest in the fields of pharmacology and toxicology. The compound is characterized by its complex molecular structure, which includes multiple rings and functional groups typical of indole derivatives. Its solubility properties and stability can vary depending on environmental conditions, such as pH and temperature. Research into Janthitrem F has focused on its biosynthesis, ecological role, and potential applications, although further studies are necessary to fully understand its mechanisms of action and implications for health and safety. As with many alkaloids, caution is advised when handling Janthitrem F due to its biological activity.

Formula: C₃₉H₅₁NO₇

InChI: InChI=1S/C39H51NO7/c1-19(41)45-29-17-26-28(46-33(29)35(4,5)43)11-12-37(8)38(9)20(10-13-39(26,37)44)14-24-22-15-23-21(16-27(22)40-32(24)38)25-18-34(2,3)47-36(6,7)30(25)31(23)42/h15-18,20,28-31,33,40,42-44H,10-14H2,1-9H3/t20-,28-,29+,30+,31+,33-,37+,38+,39+/m0/s1

InChI key: InChIKey=SHMYDSYGDWIPKT-WWVOELFWSA-N

SMILES: C[C@@]12[C@]3(C)[C@](O)(C=4[C@](CC3)(O[C@H]([C@](C)(C)O)[C@H](OC(C)=O)C4)[H])CC[C@]1(CC5=C2NC=6C5=CC7=C(C6)C=8[C@]([C@@H]7O)(C(C)(C)OC(C)(C)C8)[H])[H]

Synonyms:

• Janthitrem E monoacetate (ester)
• Janthitrem F
• 4bH-1-Benzopyrano[5′,6′:6,7]indeno[1,2-b]pyrano[4′,3′:3,4]cyclopent[1,2-f]indole-3,4b,9-triol, 2,3,5,6,6a,7,9,9a,10,12,15,15b,15c,16,17,17a-hexadecahydro-2-(1-hydroxy-1-methylethyl)-10,10,12,12,15b,15c-hexamethyl-, 3-acetate, (2S,3R,4bS,6aS,9S,9aR,15bS,15cR,17aS)-

Janthitrem F

CAS: 90986-52-0

Janthitrem F, a naphthopyran also known as 10-O-acetyljanthitrem E, is a tremorgenic mycotoxin produced by Penicillium janthinellum.

Formula: C₃₉H₅₁NO₇

Color and Shape: Solid

Molecular weight: 645.82

Ref: TM-T32261