CAS 91-02-1

2-Benzoylpyridine

Description:

2-Benzoylpyridine, with the CAS number 91-02-1, is an organic compound characterized by its pyridine ring substituted with a benzoyl group at the second position. This compound typically appears as a yellow to brown crystalline solid and is known for its aromatic properties. It has a molecular formula of C12H9NO, indicating the presence of carbon, hydrogen, nitrogen, and oxygen atoms. 2-Benzoylpyridine is soluble in organic solvents such as ethanol and acetone but has limited solubility in water. The compound exhibits notable reactivity, particularly in electrophilic aromatic substitution reactions due to the electron-withdrawing nature of the carbonyl group in the benzoyl moiety. It is often utilized in organic synthesis and as a ligand in coordination chemistry, where it can form complexes with various metal ions. Additionally, 2-benzoylpyridine has applications in the field of pharmaceuticals and agrochemicals, owing to its potential biological activities. Safety precautions should be observed when handling this compound, as it may pose health risks upon exposure.

Formula: C₁₂H₉NO

InChI: InChI=1S/C12H9NO/c14-12(10-6-2-1-3-7-10)11-8-4-5-9-13-11/h1-9H

InChI key: InChIKey=GCSHUYKULREZSJ-UHFFFAOYSA-N

SMILES: C(=O)(C1=CC=CC=C1)C2=CC=CC=N2

Synonyms:

• 1-(Pyridin-2′-yl)-phenylmethanone
• 2-Pyridyl phenyl ketone
• Ketone, phenyl 2-pyridyl
• Methanone, phenyl-2-pyridinyl-
• NSC 20887
• Phenyl 2-pyridyl ketone
• Phenyl(pyridin-2-yl)methanone
• Phenyl-2-pyridinylmethanone
• 2-Benzoylpyridine

2-Benzoylpyridine

CAS: 91-02-1

Formula: C₁₂H₉NO

Purity: >99.0%(GC)(T)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 183.21

Ref: 3B-B0304

Phenyl(pyridin-2-yl)methanone

CAS: 91-02-1

Formula: C₁₂H₉NO

Purity: 98%

Color and Shape: Solid

Molecular weight: 183.2060

Ref: IN-DA00IGDX

Phenyl(pyridin-2-yl)methanone

CAS: 91-02-1

Phenyl(pyridin-2-yl)methanone

Purity: 99%

Color and Shape: Pale Yellow Solid

Molecular weight: 183.21g/mol

Ref: 54-OR10948

Doxylamine EP Impurity D

CAS: 91-02-1

Formula: C₁₂H₉NO

Color and Shape: White To Off-White Solid

Molecular weight: 183.21

Ref: 4Z-D-3815

Phenyl(pyridin-2-yl)methanone (2-Benzoylpyridine)

Controlled Product

CAS: 91-02-1

Formula: C₁₂H₉NO

Color and Shape: Neat

Molecular weight: 183.21

Ref: 86-MM0101.04

2-Benzoylpyridine

Controlled Product

CAS: 91-02-1

Impurity Doxylamine EP Impurity D
Applications 2-Benzoylpyridine is used as a reagent to assist crosslinking in acrylic coating compounds in the polymers industry. 2-Benzoylpyridine is also a precursor for thioemicarbazone compounds that exhibit high cytotoxic activity against human leukemia cell lines and also posesses some antiinflammatory qualities.
References Hardtmann, G., et al.: J. Med. Chem., 12, 1093 (1969); Reis, D., et al.: Eur. J. Med. Chem., 45, 3904 (2010); Bassi, G., et al.: Polym. Paint. Col. J., 177, 206 (1987);

Formula: C₁₂H₉NO

Color and Shape: White

Molecular weight: 183.21

Ref: TR-B209570

Doxylamine EP Impurity D

CAS: 91-02-1

Formula: C₁₂H₉NO

Molecular weight: 183.2

Ref: ST-EA-CP-D27004

2-Benzoylpyridine

CAS: 91-02-1

2-Benzoylpyridine is a novel, potent antimicrobial compound that kills bacteria by targeting the bacterial membrane. 2-Benzoylpyridine binds to the bacterial membrane and causes leakage of ions and other molecules that disrupts the cell's redox potential. It has been shown to be active against human colon adenocarcinoma cells in vitro, with significant cytotoxicity observed. 2-Benzoylpyridine also has a coordination geometry that allows for intermolecular hydrogen bonding, which may contribute to its high potency as an antimicrobial agent.

Formula: C₁₂H₉NO

Purity: Min. 99.0 Area-%

Color and Shape: Slightly Yellow Powder

Molecular weight: 183.21 g/mol

Ref: 3D-FB34681

2-Benzoylpyridine

CAS: 91-02-1

Formula: C₁₂H₉NO

Purity: 98%

Color and Shape: White – Slightly pale yellow powder

Molecular weight: 183.21

Ref: 10-F202520