CAS 91000-69-0

FMOC-L-Arginine

Description:

FMOC-L-Arginine, with the CAS number 91000-69-0, is a derivative of the amino acid arginine, modified with a 9-fluorenylmethoxycarbonyl (FMOC) protecting group. This compound is primarily used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS), where the FMOC group serves to protect the amino group of arginine during the coupling reactions. The FMOC group is stable under basic conditions but can be easily removed under mildly acidic conditions, allowing for selective deprotection. FMOC-L-Arginine is characterized by its ability to form hydrogen bonds due to the presence of the guanidinium group in arginine, contributing to its solubility in polar solvents. Additionally, it exhibits basic properties due to the amino group, making it a key component in various biochemical applications. Its structure includes a side chain that can participate in ionic interactions, enhancing its role in protein structure and function. Overall, FMOC-L-Arginine is a valuable reagent in the field of peptide chemistry and biochemistry.

Formula: C₂₁H₂₄N₄O₄

InChI: InChI=1/C21H24N4O4/c22-20(23)24-11-5-10-18(19(26)27)25-21(28)29-12-17-15-8-3-1-6-13(15)14-7-2-4-9-16(14)17/h1-4,6-9,17-18H,5,10-12H2,(H,25,28)(H,26,27)(H4,22,23,24)/t18-/m1/s1

SMILES: c1ccc2c(c1)c1ccccc1C2COC(=N[C@H](CCCNC(=N)N)C(=O)O)O

Synonyms:

• N-alpha-9-Fluorenylmethoxycarbonyl-L-arginine
• FMOC-Arg-OH
• N~5~-(diaminomethylidene)-N~2~-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-ornithine
• N~5~-(diaminomethylidene)-N~2~-[(9H-fluoren-9-ylmethoxy)carbonyl]ornithine
• (2R)-5-[(diaminomethylidene)ammonio]-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}pentanoate

Fmoc-Arg-OH

CAS: 91000-69-0

Bachem ID: 4003163.

Formula: C₂₁H₂₄N₄O₄

Purity: 99.2%

Color and Shape: White

Molecular weight: 396.45

Ref: 01-4003163

Fmoc-L-Arginine

CAS: 91000-69-0

Formula: C₂₁H₂₄N₄O₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 396.4397

Ref: IN-DA0036VG

Fmoc-L-Arginine

CAS: 91000-69-0

Fmoc-L-Arginine

Purity: 98%

Molecular weight: 396.44g/mol

Ref: 54-OR1013366

Fmoc-Arg-OH

CAS: 91000-69-0

Fmoc-Arg-OH

Purity: ≥98%

Molecular weight: 396.44g/mol

Ref: 54-BUP18956

Fmoc-Arg-OH

CAS: 91000-69-0

Formula: C₂₁H₂₄N₄O₄

Purity: >95.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 396.45

Ref: 3B-F1360

Fmoc-Arg-OH

CAS: 91000-69-0

Formula: C₂₁H₂₄N₄O₄

Purity: ≥ 95.0%

Color and Shape: White to off-white powder or crystals

Molecular weight: 396.44

Ref: 7W-GM2318

Fmoc-Arg-OH

CAS: 91000-69-0

Fmoc-Arg-OH (Fmoc-L-Arginine) (Fmoc-L-Arginine) is a used in peptide synthesis.

Formula: C₂₁H₂₄N₄O₄

Purity: >99.99%

Color and Shape: White Solid

Molecular weight: 396.44

Ref: TM-TP1167

α-Fmoc-L-arginine

CAS: 91000-69-0

Alfa-Fmoc-L-arginine is a synthetic amino acid that has been shown to have biological properties. It is also a precursor to the industrial preparation of polymers and pharmaceuticals. Alfa-Fmoc-L-arginine has been used in studies on heart function, as it can be converted into nitric oxide, which helps regulate blood pressure and circulation. This molecule has also been shown to have an anticancer activity. The anticancer activity may be due to its ability to inhibit the production of survivin, which is an inhibitor of apoptosis. Alfa-Fmoc-L-arginine also has acidic and nucleophilic attack properties that allow it to react with carbonyl oxygens in fatty acids. This reaction leads to the formation of a molecule with two carboxylic acids which are polar molecules that are soluble in water.

Formula: C₂₁H₂₄N₄O₄

Purity: Min. 95%

Color and Shape: Solid

Molecular weight: 396.44 g/mol

Ref: 3D-FA39700

Fmoc-Arg-OH

CAS: 91000-69-0

M03403 - Fmoc-Arg-OH

Formula: C₂₁H₂₄N₄O₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 396.447

Ref: 10-M03403

FMOC-L-Arginine extrapure, 98%

CAS: 91000-69-0

Formula: C₂₁H₂₄N₄O₄

Purity: min. 98%

Color and Shape: White, Crystalline powder

Molecular weight: 396.45

Ref: SR-88459

N α-Fmoc-L-arginine

CAS: 91000-69-0

Applications Nα-Fmoc-L-arginine is an N-Fmoc-protected form of L-Arginine (A769505). L-Arginine is an conditionally essential amino acid for humans and adult mammals as it’s requirements exceed production during certain developmental stages in life (such as pregnancy). L-Arginine also prevents blood toxicity from intravenous amino acid administration in humans.
References Bronte, V. & Zanovello, P.: Nat. Rev. Immun., 5, 641 (2005); Fahey, J.: J .Clin. Invest., 36, 1647 (1957)

Formula: C₂₁H₂₄N₄O₄

Color and Shape: Neat

Molecular weight: 396.44

Ref: TR-F620905