Deuterated Crosslinker DSG-d4, with the CAS number 910292-86-3, is a chemical compound used primarily in bioconjugation and protein labeling applications. It is a deuterated version of the crosslinker DSG (Disuccinimidyl Glutarate), which is known for its ability to form stable covalent bonds between biomolecules, such as proteins and peptides. The presence of deuterium, a stable isotope of hydrogen, enhances the compound's utility in mass spectrometry and NMR spectroscopy, allowing for more precise tracking and analysis of biomolecular interactions. DSG-d4 features two reactive N-hydroxysuccinimide (NHS) ester groups that facilitate the formation of amide bonds with primary amines in proteins. This crosslinker is particularly valuable in studies involving protein-protein interactions, structural biology, and the development of bioconjugates for therapeutic applications. Its deuterated nature also helps in reducing background noise in analytical techniques, making it a preferred choice for researchers seeking high sensitivity and specificity in their experiments.

Deuterated Crosslinker DSG-d4

910292-86-3: Deuterated Crosslinker DSG-d4, with the CAS number 910292-86-3, is a chemical compound used primarily in bioconjugation and protein labeling applications. It is a deuterated version of the crosslinker DSG (Disuccinimidyl Glutarate), which is known for its ability to form stable covalent bonds between biomolecules, such as proteins and peptides. The presence of deuterium, a stable isotope of hydrogen, enhances the compound's utility in mass spectrometry and NMR spectroscopy, allowing for more precise tracking and analysis of biomolecular interactions. DSG-d4 features two reactive N-hydroxysuccinimide (NHS) ester groups that facilitate the formation of amide bonds with primary amines in proteins. This crosslinker is particularly valuable in studies involving protein-protein interactions, structural biology, and the development of bioconjugates for therapeutic applications. Its deuterated nature also helps in reducing background noise in analytical techniques, making it a preferred choice for researchers seeking high sensitivity and specificity in their experiments.

<p>Applications Glutaric Acid-d4 Bis(3-Sulfo-N-hydroxysuccinimide Ester) is an isotope labelled water soluble and cell membrane impermeable crosslinking agent. Glutaric Acid-d4 Bis(3-Sulfo-N-hydroxysuccinimide Ester) was used in studies of insulin crosslinking to insulin receptors.<br>References Bezouska, K., et al.: Biocon. Chem., 23, 2032 (2012); Mealman, T.D., et al.: Biochem., 50, 2559 (2011); Waugh, S.M., et al.: Biochem., 28, 3448 (1989);<br></p>

CAS 910292-86-3

Deuterated Crosslinker DSG-d4

Glutaric Acid-d4 Bis(3-Sulfo-N-hydroxysuccinimide Ester) Disodium Salt

Ref: TR-G598080